Kalins'ka L M, Miestiechkina A Ia
Ukr Biokhim Zh. 1975 May-Jun;47(3):314-8.
A single introduction of hydrocortisone is established to evoke an increase in the total activity of acid peptide-hydrolase in most areas of the brain. A single administration of ACTH single and long term administration of hydrocortisone was found to increase the specific activity of acid peptide-hydrolase of the soluble fraction. The specific activity of neutral peptide-hydrolase of the soluble fraction increases with a single administration of ACTH and long term administration of hydrocortisone. A single and long term administration of hydrocortisone and ACTH cause an increase in the percentage of the soluble form of peptide-hydrolases of the total activity.
已证实单次注射氢化可的松可引起大脑大多数区域酸性肽水解酶的总活性增加。单次注射促肾上腺皮质激素（ACTH）以及长期注射氢化可的松均被发现可提高可溶性部分酸性肽水解酶的比活性。可溶性部分中性肽水解酶的比活性在单次注射ACTH以及长期注射氢化可的松后会增加。氢化可的松和ACTH的单次及长期注射会导致肽水解酶可溶性形式在总活性中的百分比增加。
