Mestechkina A Ia, Mishunina T M
Ukr Biokhim Zh. 1977 Jan-Feb;49(1):72-7.
Hydrocortisone and ACTH administration induced AlT- and AsT-activity changes in the brain hemispheres, liver, spleen, muscles and blood plasm of rabbits. The direction and rate of changes of the studied enzymes activity in the tissues was not the same after hydrocortisone and ACTH injections and depended on duration of the hormones administration. The changes in the AlT-activity were more essential than those in the AsT-activity for all tissues.
氢化可的松和促肾上腺皮质激素的给药引起了家兔大脑半球、肝脏、脾脏、肌肉和血浆中谷丙转氨酶(ALT)和谷草转氨酶(AST)活性的变化。氢化可的松和促肾上腺皮质激素注射后,所研究组织中这些酶活性的变化方向和速率并不相同,且取决于激素给药的持续时间。对于所有组织而言,ALT活性的变化比AST活性的变化更为显著。