Froehler Michael T, Geocadin Romergryko G
Department of Neurology, Johns Hopkins Hospital, 600 N. Wolfe Street, Meyer 8-140, Baltimore, MD 21287, USA.
J Neurol Sci. 2007 Oct 15;261(1-2):118-26. doi: 10.1016/j.jns.2007.04.042. Epub 2007 Jun 7.
Therapeutic hypothermia is a proven part of cardio-cerebral resuscitation after cardiac arrest as it improves neurologic outcomes after hypoxic brain injury. This article reviews the mechanisms of hypothermic neuroprotection, the clinical trials that support its use after cardiac arrest, as well as the impact of hypothermia on patient management and prognosis. In caring for patients suffering hypoxic brain injury after cardiac arrest, the role of the neurologist is no longer limited to prognosis but is now to become actively involved in clinical management which includes the use of therapeutic hypothermia.
治疗性低温是心脏骤停后心肺复苏的一个已被证实的部分，因为它能改善缺氧性脑损伤后的神经学转归。本文综述了低温神经保护的机制、支持其在心脏骤停后应用的临床试验，以及低温对患者管理和预后的影响。在护理心脏骤停后发生缺氧性脑损伤的患者时，神经科医生的作用不再局限于预后判断，而是要积极参与临床管理，其中包括使用治疗性低温。
