Ponsky Todd, Hindle Anna, Sandler Anthony
Children's National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010-2970, USA.
Surg Clin North Am. 2007 Jun;87(3):643-58. doi: 10.1016/j.suc.2007.03.002.
Inflammatory bowel disease (IBD) is a general term used to describe two chronic bowel disorders, Crohn's disease (CD) and ulcerative colitis (UC), both of which are characterized by autoimmune-related inflammation of the intestines. UC is limited to the colonic mucosa, whereas CD can involve any part of the intestinal tract from the mouth to the anus. The true etiology of UC and CD is still unknown, although extensive research has identified some genetic and environmental factors. This article discusses current clinical concepts of both diseases in the pediatric population.
炎症性肠病(IBD)是一个用于描述两种慢性肠道疾病的通用术语,即克罗恩病(CD)和溃疡性结肠炎(UC),这两种疾病均以肠道自身免疫相关炎症为特征。UC局限于结肠黏膜,而CD可累及从口腔到肛门的肠道任何部位。尽管广泛研究已确定了一些遗传和环境因素,但UC和CD的真正病因仍不清楚。本文讨论了这两种疾病在儿科人群中的当前临床概念。