活体肝移植右肝叶供体的严重精神问题。
Severe psychiatric problems in right hepatic lobe donors for living donor liver transplantation.
作者信息
Trotter James F, Hill-Callahan Margaret M, Gillespie Brenda W, Nielsen Carrie A, Saab Sammy, Shrestha Roshan, Talamantes Michael M, Weinrieb Robert M
机构信息
Department of Surgery, University of Colorado, Denver, CO 80262, and Department of Transplant Services, Piedmont Hospital, Atlanta, GA, USA.
出版信息
Transplantation. 2007 Jun 15;83(11):1506-8. doi: 10.1097/01.tp.0000263343.21714.3b.
BACKGROUND
The morbidity and mortality from donation of a right hepatic lobe for living donor liver transplantation (LDLT) is an important issue for this procedure. We report the prevalence of severe psychiatric postoperative complications from the Adult-to-Adult Living Donor Liver Transplantation Cohort study (A2ALL), which was established to define the risks and benefits of LDLT for donors and recipients.
METHODS
Severe psychiatric complications were evaluated in all donors from the A2ALL study who were evaluated between 1998 and February 2003.
RESULTS
Of the 392 donors, 16 (4.1%) had one or multiple psychiatric complications, including three severe psychiatric complications (suicide, accidental drug overdose, and suicide attempt).
CONCLUSIONS
Despite extensive preoperative screening, some donors experience severe psychiatric complications, including suicide, after liver donation. Psychiatric assessment and monitoring of liver donors may help to understand and prevent such tragic events.
背景
活体供肝肝移植（LDLT）中右肝叶供肝的发病率和死亡率是该手术的一个重要问题。我们报告了成人对成人活体供肝肝移植队列研究（A2ALL）中严重精神科术后并发症的发生率，该研究旨在确定LDLT对供体和受体的风险与益处。
方法
对1998年至2003年2月期间接受评估的A2ALL研究中的所有供体进行严重精神科并发症评估。
结果
在392名供体中，16名（4.1%）出现一种或多种精神科并发症，包括三种严重精神科并发症（自杀、意外药物过量和自杀未遂）。
结论
尽管进行了广泛的术前筛查，但一些供体在肝捐赠后仍会出现包括自杀在内的严重精神科并发症。对肝供体进行精神科评估和监测可能有助于理解和预防此类悲剧事件。
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