• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童支气管哮喘中氧自由基作用的研究

Examination of the role of oxygen free radicals in bronchial asthma in childhood.

作者信息

Novák Z, Németh I, Gyurkovits K, Varga S I, Matkovics B

机构信息

County and Municipal Children's Hospital, Szeged, Hungary.

出版信息

Clin Chim Acta. 1991 Sep 30;201(3):247-51. doi: 10.1016/0009-8981(91)90375-m.

DOI:10.1016/0009-8981(91)90375-m
PMID:1756597
Abstract

The antioxidant enzyme activities, the lipid peroxidation level, the parameters of glutathione metabolism, and the proportion of haemoglobin oxidation products were determined during the symptom-free period of childhood bronchial asthma. A decreased catalase activity and a significantly reduced glutathione instability were demonstrated as compared to the controls. The results indicate that antioxidant protection of the haemoglobin molecule in asthmatic children is considerably decreased.

摘要

在儿童支气管哮喘无症状期测定了抗氧化酶活性、脂质过氧化水平、谷胱甘肽代谢参数以及血红蛋白氧化产物比例。与对照组相比,过氧化氢酶活性降低,谷胱甘肽不稳定性显著降低。结果表明,哮喘儿童血红蛋白分子的抗氧化保护作用明显降低。

相似文献

1
Examination of the role of oxygen free radicals in bronchial asthma in childhood.儿童支气管哮喘中氧自由基作用的研究
Clin Chim Acta. 1991 Sep 30;201(3):247-51. doi: 10.1016/0009-8981(91)90375-m.
2
Excessive free radical generation in the blood of children suffering from asthma.患有哮喘的儿童血液中自由基生成过多。
Clin Chim Acta. 2001 Mar;305(1-2):107-14. doi: 10.1016/s0009-8981(00)00425-3.
3
Lipid peroxidation and haemoglobin degradation in red blood cells exposed to t-butyl hydroperoxide. The relative roles of haem- and glutathione-dependent decomposition of t-butyl hydroperoxide and membrane lipid hydroperoxides in lipid peroxidation and haemolysis.暴露于叔丁基过氧化氢的红细胞中的脂质过氧化和血红蛋白降解。叔丁基过氧化氢和膜脂质氢过氧化物的血红素依赖性和谷胱甘肽依赖性分解在脂质过氧化和溶血中的相对作用。
Biochem J. 1983 Jun 15;212(3):759-72. doi: 10.1042/bj2120759.
4
Oxidant-antioxidant imbalance in the erythrocytes of sporadic amyotrophic lateral sclerosis patients correlates with the progression of disease.散发性肌萎缩侧索硬化症患者红细胞中的氧化-抗氧化失衡与疾病进展相关。
Neurochem Int. 2008 May;52(6):1284-9. doi: 10.1016/j.neuint.2008.01.009. Epub 2008 Jan 20.
5
Thyroid hormone-induced haemoglobin changes and antioxidant enzymes response in erythrocytes.甲状腺激素诱导的血红蛋白变化和红细胞抗氧化酶反应。
Cell Biochem Funct. 2011 Jul;29(5):408-13. doi: 10.1002/cbf.1765. Epub 2011 May 16.
6
A comprehensive study of oxidative stress and antioxidant status in preeclampsia and normal pregnancy.子痫前期和正常妊娠中氧化应激与抗氧化状态的综合研究。
Free Radic Biol Med. 2004 Aug 15;37(4):557-70. doi: 10.1016/j.freeradbiomed.2004.04.035.
7
[Serum paraoxonase activity, total antioxidant potential and lipid peroxidation products in children with bronchial asthma exacerbation].[支气管哮喘急性加重期患儿的血清对氧磷酶活性、总抗氧化能力及脂质过氧化产物]
Wiad Lek. 2002;55(5-6):257-63.
8
Enzymatic efficiency of erythrocyte antioxidant barrier and lipid peroxidation in children from families with high risk of early atherosclerosis.早期动脉粥样硬化高危家庭儿童红细胞抗氧化屏障的酶活性及脂质过氧化情况
Med Sci Monit. 2000 Jan-Feb;6(1):112-6.
9
Erythrocyte antioxidants and membrane vulnerability.
J Lab Clin Med. 1986 May;107(5):401-4.
10
[Age characteristics of free radical oxidation of lipids and antioxidant defence in erythrocytes from healthy individuals].
Klin Lab Diagn. 2003 Aug(8):17-8.

引用本文的文献

1
Antioxidant defense enzyme genes and asthma susceptibility: gender-specific effects and heterogeneity in gene-gene interactions between pathogenetic variants of the disease.抗氧化防御酶基因与哮喘易感性:疾病致病变异之间基因-基因相互作用的性别特异性效应和异质性
Biomed Res Int. 2014;2014:708903. doi: 10.1155/2014/708903. Epub 2014 May 5.
2
Nitric oxide metabolism in asthma pathophysiology.哮喘病理生理学中的一氧化氮代谢
Biochim Biophys Acta. 2011 Nov;1810(11):1008-16. doi: 10.1016/j.bbagen.2011.06.009. Epub 2011 Jun 21.
3
Redox control of asthma: molecular mechanisms and therapeutic opportunities.
氧化还原调控与哮喘:分子机制与治疗机遇。
Antioxid Redox Signal. 2010 Jan;12(1):93-124. doi: 10.1089/ars.2008.2425.
4
Lipid peroxidation in bronchial asthma.支气管哮喘中的脂质过氧化作用。
Indian J Pediatr. 2003 Sep;70(9):715-7. doi: 10.1007/BF02724313.