Novák Z, Németh I, Gyurkovits K, Varga S I, Matkovics B
County and Municipal Children's Hospital, Szeged, Hungary.
Clin Chim Acta. 1991 Sep 30;201(3):247-51. doi: 10.1016/0009-8981(91)90375-m.
The antioxidant enzyme activities, the lipid peroxidation level, the parameters of glutathione metabolism, and the proportion of haemoglobin oxidation products were determined during the symptom-free period of childhood bronchial asthma. A decreased catalase activity and a significantly reduced glutathione instability were demonstrated as compared to the controls. The results indicate that antioxidant protection of the haemoglobin molecule in asthmatic children is considerably decreased.
在儿童支气管哮喘无症状期测定了抗氧化酶活性、脂质过氧化水平、谷胱甘肽代谢参数以及血红蛋白氧化产物比例。与对照组相比,过氧化氢酶活性降低,谷胱甘肽不稳定性显著降低。结果表明,哮喘儿童血红蛋白分子的抗氧化保护作用明显降低。