Richetta A, Amoruso G F, Ascoli V, Natale M E, Carboni V, Carlomagno V, Pezza M, Cimillo M, Maiani E, Mattozzi C, Calvieri S
Department of Dermatology and Plastic Surgery, University of Rome "La Sapienza", Rome, Italy.
Clin Ter. 2007 Mar-Apr;158(2):151-5.
We described a case report of a 36-year-old woman with a 10-year-history of idiopathic CD4+ T-lymphocitopenia and Kaposi's sarcoma HHV8+ who developed recurrent pleural effusion. Laboratory and instrumental tests with morphologic, immunophenotypic and molecular analysis of pleural sediment suggest us the diagnosis of primary effusion lymphoma (PEL). The term primary effusion lymphoma defines an extranodal non-Hodgkin's lymphoma HHV8-related, usually classified as a B-cell lymphoma, that grows in liquid-phase within body cavities. The case reported by the Authors appears to be of great interest for its epidemiological and clinical features.
我们描述了一例病例报告，患者为一名36岁女性，有10年特发性CD4 + T淋巴细胞减少症病史，患有HHV8阳性的卡波西肉瘤，出现复发性胸腔积液。对胸腔积液沉淀物进行形态学、免疫表型和分子分析的实验室及仪器检查提示我们诊断为原发性渗出性淋巴瘤（PEL）。原发性渗出性淋巴瘤这一术语定义了一种与HHV8相关的结外非霍奇金淋巴瘤，通常归类为B细胞淋巴瘤，在体腔内以液相形式生长。作者报告的该病例因其流行病学和临床特征似乎极具研究价值。
