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红曲米对高胆固醇血症患者降低血脂比例的疗效。

Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients.

作者信息

Huang Chien-Fang, Li Tsai-Chung, Lin Cheng-Chieh, Liu Chiu-Shong, Shih Hung-Chang, Lai Ming-May

机构信息

Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan, Republic of China.

出版信息

Eur J Cardiovasc Prev Rehabil. 2007 Jun;14(3):438-40. doi: 10.1097/HJR.0b013e32801da137.

DOI:10.1097/HJR.0b013e32801da137
PMID:17568245
Abstract

BACKGROUND

Several lipid ratios may be predictors of coronary artery disease risk. We assessed the efficacy of Monascus purpureus Went rice (red yeast rice) on lowering lipid ratios.

METHOD AND RESULTS

We evaluated 79 hypercholesterolemic patients (aged 23-65 years) who received a twice-daily dose of either red yeast rice or a placebo at 600 mg for 8 weeks. The 8-week treatment with red yeast rice showed significantly greater reduction than the placebo treatment in low-density lipoprotein cholesterol levels, total cholesterol/high-density lipoprotein cholesterol, low-density lipoprotein cholesterol/high-density lipoprotein cholesterol and apolipoprotein B/apolipoprotein A-I ratios.

CONCLUSIONS

Red yeast rice can reduce lipid ratios in hypercholesterolemic patients.

摘要

背景

几种脂质比率可能是冠状动脉疾病风险的预测指标。我们评估了红曲米对降低脂质比率的功效。

方法与结果

我们评估了79名高胆固醇血症患者(年龄23 - 65岁),他们每天两次服用红曲米或600毫克安慰剂,为期8周。与安慰剂治疗相比,8周的红曲米治疗在低密度脂蛋白胆固醇水平、总胆固醇/高密度脂蛋白胆固醇、低密度脂蛋白胆固醇/高密度脂蛋白胆固醇以及载脂蛋白B/载脂蛋白A - I比率方面显示出显著更大的降低幅度。

结论

红曲米可降低高胆固醇血症患者的脂质比率。

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