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用于全身皮肤电子线治疗(TSET)的电子束的体内EBT放射变色胶片剂量测定法。

In vivo EBT radiochromic film dosimetry of electron beam for Total Skin Electron Therapy (TSET).

作者信息

Bufacchi A, Carosi A, Adorante N, Delle Canne S, Malatesta T, Capparella R, Fragomeni R, Bonanni A, Leone M, Marmiroli L, Begnozzi L

机构信息

AFaR U.O.C. Fisica Sanitaria, Ospedale S. Giovanni Calibita Fatebenefratelli, Isola Tiberina, 39, 00186 Rome, Italy.

出版信息

Phys Med. 2007 Jun;23(2):67-72. doi: 10.1016/j.ejmp.2007.03.003. Epub 2007 May 23.

Abstract

EBT radiochromic films were used to determine skin-dose maps for patients undergone Total Skin Electron Therapy (TSET). Gafchromic EBT radiochromic film is one of the newest radiation-induced auto-developing photon and electron-beam analysis films available for therapeutic radiation dosimetry in radiotherapy applications. EBT films can be particularly useful in TSET; due to patient morphology, underdosed regions typically occur, and the radiochromic film represents a suitable candidate for monitoring them. In this study, TSET was applied to treat cutaneous T-cell lymphoma. The technique for TSET was implemented by using an electron beam with a nominal energy of 6MeV. The patient was treated in a standing position using dual angled fields in order to obtain the greatest dose uniformity along the patient's longitudinal axis. The electron beam energy was degraded by a PMMA filter. The in vivo dose distribution was determined through the use of EBT films, as well as of thermoluminescent dosimeters for comparison (TLDs). EBT results showed a reasonable agreement with TLDs data.

摘要

使用EBT放射变色胶片来确定接受全身皮肤电子线治疗(TSET)患者的皮肤剂量分布图。Gafchromic EBT放射变色胶片是用于放射治疗应用中治疗性放射剂量测定的最新的辐射诱导自动显影光子和电子束分析胶片之一。EBT胶片在TSET中可能特别有用;由于患者的形态,通常会出现剂量不足的区域,而放射变色胶片是监测这些区域的合适选择。在本研究中,TSET用于治疗皮肤T细胞淋巴瘤。TSET技术通过使用标称能量为6MeV的电子束来实施。患者采用站立姿势,使用双角度野进行治疗,以便沿患者的纵轴获得最大的剂量均匀性。电子束能量通过PMMA滤过器衰减。通过使用EBT胶片以及用于比较的热释光剂量计(TLD)来确定体内剂量分布。EBT结果与TLD数据显示出合理的一致性。

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