全身皮肤电子束治疗期间体内剂量测定结果的回顾。
Review of the results of the in vivo dosimetry during total skin electron beam therapy.
作者信息
Guidi Gabriele, Gottardi Giovanni, Ceroni Paola, Costi Tiziana
机构信息
Department of Medical Physics, Az. Ospedaliero-Universitaria di Modena, Modena, Italy.
出版信息
Rep Pract Oncol Radiother. 2013 Aug 15;19(2):144-50. doi: 10.1016/j.rpor.2013.07.011. eCollection 2014 Mar.
Abstract
This work reviews results of in vivo dosimetry (IVD) for total skin electron beam (TSEB) therapy, focusing on new methods, data emerged within 2012. All quoted data are based on a careful review of the literature reporting IVD results for patients treated by means of TSEB therapy. Many of the reviewed papers refer mainly to now old studies and/or old guidelines and recommendations (by IAEA, AAPM and EORTC), because (due to intrinsic rareness of TSEB-treated pathologies) only a limited number of works and reports with a large set of numerical data and proper statistical analysis is up-to-day available in scientific literature. Nonetheless, a general summary of the results obtained by the now numerous IVD techniques available is reported; innovative devices and methods, together with areas of possible further and possibly multicenter investigations for TSEB therapies are highlighted.
摘要
本研究综述了全身皮肤电子束（TSEB）治疗的体内剂量测定（IVD）结果，重点关注2012年以来出现的新方法和数据。所有引用的数据均基于对有关TSEB治疗患者IVD结果的文献的仔细回顾。许多被综述的论文主要参考的是现在已过时的研究和/或旧的指南与建议（由国际原子能机构、美国医学物理学家协会和欧洲癌症研究与治疗组织发布），因为（由于接受TSEB治疗的病症本身罕见）科学文献中目前仅有数量有限的包含大量数值数据和适当统计分析的研究与报告。尽管如此，本文还是报告了现有众多IVD技术所取得结果的总体概述；突出介绍了创新设备和方法，以及TSEB治疗可能进一步开展的、可能涉及多中心研究的领域。
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