Levey A S, Atkins R, Coresh J, Cohen E P, Collins A J, Eckardt K-U, Nahas M E, Jaber B L, Jadoul M, Levin A, Powe N R, Rossert J, Wheeler D C, Lameire N, Eknoyan G
Tufts-New England Medical Center, Boston, Massachusetts, USA.
Kidney Int. 2007 Aug;72(3):247-59. doi: 10.1038/sj.ki.5002343. Epub 2007 Jun 13.
Chronic kidney disease (CKD) is increasingly recognized as a global public health problem. There is now convincing evidence that CKD can be detected using simple laboratory tests, and that treatment can prevent or delay complications of decreased kidney function, slow the progression of kidney disease, and reduce the risk of cardiovascular disease (CVD). Translating these advances to simple and applicable public health measures must be adopted as a goal worldwide. Understanding the relationship between CKD and other chronic diseases is important to developing a public health policy to improve outcomes. The 2004 Kidney Disease Improving Global Outcomes (KDIGO) Controversies Conference on 'Definition and Classification of Chronic Kidney Disease' represented an important endorsement of the Kidney Disease Outcome Quality Initiative definition and classification of CKD by the international community. The 2006 KDIGO Controversies Conference on CKD was convened to consider six major topics: (1) CKD classification, (2) CKD screening and surveillance, (3) public policy for CKD, (4) CVD and CVD risk factors as risk factors for development and progression of CKD, (5) association of CKD with chronic infections, and (6) association of CKD with cancer. This report contains the recommendations from the meeting. It has been reviewed by the conference participants and approved as position statement by the KDIGO Board of Directors. KDIGO will work in collaboration with international and national public health organizations to facilitate implementation of these recommendations.
慢性肾脏病(CKD)日益被视为一个全球性的公共卫生问题。现在有令人信服的证据表明,使用简单的实验室检测就能发现CKD,而且治疗可以预防或延缓肾功能下降的并发症,减缓肾病进展,并降低心血管疾病(CVD)风险。必须将这些进展转化为简单且适用的公共卫生措施,并将其作为全球范围内的目标。了解CKD与其他慢性疾病之间的关系对于制定改善治疗效果的公共卫生政策很重要。2004年全球改善肾脏病预后组织(KDIGO)关于“慢性肾脏病的定义和分类”的争议会议,标志着国际社会对肾脏病预后质量倡议组织关于CKD的定义和分类的重要认可。2006年KDIGO关于CKD的争议会议召开以审议六个主要议题:(1)CKD分类;(2)CKD筛查和监测;(3)CKD公共政策;(4)作为CKD发生和进展风险因素的CVD及CVD风险因素;(5)CKD与慢性感染的关联;(6)CKD与癌症的关联。本报告包含了会议的建议。它已经过会议参与者审阅,并被KDIGO董事会批准为立场声明。KDIGO将与国际和国家公共卫生组织合作,以促进这些建议的实施。