McCabe Sean Esteban, West Brady T, Wechsler Henry
University of Michigan, Substance Abuse Research Center, 2025 Traverwood Drive, Suite C, Ann Arbor, Michigan 48105-2194, USA.
J Stud Alcohol Drugs. 2007 Jul;68(4):543-7. doi: 10.15288/jsad.2007.68.543.
The purpose of this study was to examine the association between Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), alcohol-use disorders (AUDs) and nonmedical use of prescription drugs (NMPD) among U.S. college students. A secondary aim of this study was to identify individual-level and college-level characteristics associated with the co-occurrence of AUDs and NMPD.
Data were collected from self-administered mail surveys, sent to a random sample of approximately 14,000 college students from a nationally representative sample of 119 U.S. colleges and universities.
Among U.S. college students, those with AUDs represented approximately 75% of nonmedical users of prescription drugs. Multivariate logistic regression analyses indicated that college students with past-year DSM-IV alcohol abuse only (adjusted odds ratio [AOR]=4.46, 95% confidence interval [CI]=3.59-5.55) and students with past-year DSM-IV alcohol dependence (AOR=9.17, 95% CI=7.05-11.93) had significantly increased odds of NMPD in the past year compared with students without AUDs. The co-occurrence of AUDs and NMPD was more likely among college students who were male, white, earned lower grade point averages, and attended co-ed colleges and institutions located in Southern or Northeastern U.S. regions.
The findings provide evidence that NMPD is more prevalent among those college students with AUDs, especially individuals with past-year DSM-IV alcohol dependence. The assessment and treatment of AUDs among college students should account for other forms of drug use such as NMPD.
本研究旨在探讨美国大学生中《精神疾病诊断与统计手册》第四版(DSM-IV)酒精使用障碍(AUDs)与非医疗目的使用处方药(NMPD)之间的关联。本研究的第二个目的是确定与AUDs和NMPD共现相关的个体层面和大学层面的特征。
数据通过自填式邮件调查收集,发送给来自美国119所高校具有全国代表性样本中的约14000名大学生的随机样本。
在美国大学生中,患有AUDs的学生约占非医疗目的使用处方药学生的75%。多因素逻辑回归分析表明,与无AUDs的学生相比,仅过去一年有DSM-IV酒精滥用的大学生(校正比值比[AOR]=4.46,95%置信区间[CI]=3.59 - 5.55)以及过去一年有DSM-IV酒精依赖的学生(AOR=9.17,95% CI=7.05 - 11.93)在过去一年中NMPD的发生几率显著增加。AUDs和NMPD的共现在美国南部或东北部地区的男性、白人、平均绩点较低且就读于男女同校院校的大学生中更为常见。
研究结果表明,NMPD在患有AUDs的大学生中更为普遍,尤其是过去一年有DSM-IV酒精依赖的个体。对大学生AUDs的评估和治疗应考虑其他形式的药物使用,如NMPD。