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美国大学生中的酒精使用障碍和处方药的非医疗用途。

Alcohol-use disorders and nonmedical use of prescription drugs among U.S. college students.

作者信息

McCabe Sean Esteban, West Brady T, Wechsler Henry

机构信息

University of Michigan, Substance Abuse Research Center, 2025 Traverwood Drive, Suite C, Ann Arbor, Michigan 48105-2194, USA.

出版信息

J Stud Alcohol Drugs. 2007 Jul;68(4):543-7. doi: 10.15288/jsad.2007.68.543.

Abstract

OBJECTIVE

The purpose of this study was to examine the association between Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), alcohol-use disorders (AUDs) and nonmedical use of prescription drugs (NMPD) among U.S. college students. A secondary aim of this study was to identify individual-level and college-level characteristics associated with the co-occurrence of AUDs and NMPD.

METHOD

Data were collected from self-administered mail surveys, sent to a random sample of approximately 14,000 college students from a nationally representative sample of 119 U.S. colleges and universities.

RESULTS

Among U.S. college students, those with AUDs represented approximately 75% of nonmedical users of prescription drugs. Multivariate logistic regression analyses indicated that college students with past-year DSM-IV alcohol abuse only (adjusted odds ratio [AOR]=4.46, 95% confidence interval [CI]=3.59-5.55) and students with past-year DSM-IV alcohol dependence (AOR=9.17, 95% CI=7.05-11.93) had significantly increased odds of NMPD in the past year compared with students without AUDs. The co-occurrence of AUDs and NMPD was more likely among college students who were male, white, earned lower grade point averages, and attended co-ed colleges and institutions located in Southern or Northeastern U.S. regions.

CONCLUSIONS

The findings provide evidence that NMPD is more prevalent among those college students with AUDs, especially individuals with past-year DSM-IV alcohol dependence. The assessment and treatment of AUDs among college students should account for other forms of drug use such as NMPD.

摘要

目的

本研究旨在探讨美国大学生中《精神疾病诊断与统计手册》第四版(DSM-IV)酒精使用障碍(AUDs)与非医疗目的使用处方药(NMPD)之间的关联。本研究的第二个目的是确定与AUDs和NMPD共现相关的个体层面和大学层面的特征。

方法

数据通过自填式邮件调查收集,发送给来自美国119所高校具有全国代表性样本中的约14000名大学生的随机样本。

结果

在美国大学生中,患有AUDs的学生约占非医疗目的使用处方药学生的75%。多因素逻辑回归分析表明,与无AUDs的学生相比,仅过去一年有DSM-IV酒精滥用的大学生(校正比值比[AOR]=4.46,95%置信区间[CI]=3.59 - 5.55)以及过去一年有DSM-IV酒精依赖的学生(AOR=9.17,95% CI=7.05 - 11.93)在过去一年中NMPD的发生几率显著增加。AUDs和NMPD的共现在美国南部或东北部地区的男性、白人、平均绩点较低且就读于男女同校院校的大学生中更为常见。

结论

研究结果表明,NMPD在患有AUDs的大学生中更为普遍,尤其是过去一年有DSM-IV酒精依赖的个体。对大学生AUDs的评估和治疗应考虑其他形式的药物使用,如NMPD。

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