Peluso F, Goldner F
Department of Medicine, Brooke Army Medical Center, San Antonio, Texas 78234-6200.
Gastrointest Endosc. 1991 Nov-Dec;37(6):604-6. doi: 10.1016/s0016-5107(91)70863-8.
Although the hot biopsy technique is widely used to treat diminutive colon polyps, there is concern over its efficacy and safety. Our study involved 39 patients undergoing routine colonoscopy in whom 62 diminutive polyps were found in the rectosigmoid. These lesions were treated with hot biopsy forceps in the standard manner. Flexible sigmoidoscopy was repeated 1 and 2 weeks later with the original treatment sites being identified. Eleven of the 62 sites (17%) revealed persistent viable polyp remnants, indicating incomplete treatment. In terms of safety, there were no clinical complications in this small study and most post-biopsy ulcers were healed by 2 weeks. This study shows that the hot biopsy technique may be unreliable in eradicating diminutive colon polyps.
尽管热活检技术被广泛用于治疗微小结肠息肉，但人们对其疗效和安全性仍存在担忧。我们的研究纳入了39例行常规结肠镜检查的患者，在其直肠乙状结肠部位发现了62个微小息肉。这些病变采用标准方式用热活检钳进行治疗。1周和2周后重复进行乙状结肠镜检查，确定原治疗部位。62个部位中有11个（17%）显示存在持续存活的息肉残余，表明治疗不彻底。在安全性方面，这项小型研究中未出现临床并发症，大多数活检后溃疡在2周内愈合。本研究表明，热活检技术在根除微小结肠息肉方面可能不可靠。
