Ochsner H, Hauser B, Zrenner E
Abteilung und Lehrstuhl für Pathophysiologie, Universitäts-Augenklinik, Tübingen, Bundesrepublik Deutschland.
Fortschr Ophthalmol. 1991;88(5):549-53.
Intolerance to bright light is a nonspecific ophthalmological symptom, originating either in disturbances of the optic apparatus of the eye or caused by functional disturbances of the neuronal network of the retina. Disturbances in brightness and darkness adaptation can often cause considerable decrease in visual acuity, which is not evident in the standardized tests that measure photophobia in conjunction with visual function. If the test field is very bright and the patient has photophobia, the visual acuity is often reduced considerably. The relationship between visual acuity and luminance of the test field was determined in glare--sensitive patients using a relatively simple method and a large range of luminances (0.1-30,000 cd/m2). In contrast to previously used methods, visual acuity was determined in a range where neuronal mechanism can be expected to be responsible for adaptation to brightness. We found disturbances in the relationship between visual acuity and luminance in several diseases, and it was especially pronounced in cone dystrophies. Affections of the optic nerve and opacities of the optic media usually did not cause a marked decrease in visual acuity at high luminances. As a supplemental investigation to mesoptometry and nyctometry, the method described here primarily permits types of photophobia to be determined that are not caused by stray light. The dynamic nature of neuronal adaptation processes determined by this test has therefore considerable influence on visual acuity.
对强光不耐受是一种非特异性眼科症状,其起因要么是眼部视觉器官的紊乱,要么是由视网膜神经网络的功能紊乱引起。明暗适应的紊乱常常会导致视力显著下降,而在结合视觉功能测量畏光的标准化测试中,这种下降并不明显。如果测试视野非常明亮且患者有畏光症状,视力往往会大幅降低。使用一种相对简单的方法并在较大范围的亮度(0.1 - 30,000 cd/m²)下,测定了畏光敏感患者的视力与测试视野亮度之间的关系。与先前使用的方法不同,视力是在一个可预期神经元机制负责亮度适应的范围内测定的。我们在几种疾病中发现了视力与亮度之间关系的紊乱,在视锥细胞营养不良中尤为明显。视神经病变和视路混浊通常在高亮度下不会导致视力显著下降。作为对中光度测量法和暗适应测量法的补充研究,这里描述的方法主要可以确定并非由杂散光引起的畏光类型。因此,该测试所确定的神经元适应过程的动态性质对视力有相当大的影响。