市售B族链球菌乳胶凝集试验的比较
Comparison of commercially available group B streptococcal latex agglutination assays.
作者信息
Ascher D P, Wilson S, Fischer G W
机构信息
Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799.
出版信息
J Clin Microbiol. 1991 Dec;29(12):2895-6. doi: 10.1128/jcm.29.12.2895-2896.1991.
Abstract
Detection of group B streptococcus (GBS) antigen in urine by latex particle agglutination (LPA) may facilitate the rapid diagnosis of GBS sepsis. We sought to compare three commercial LPA assays with specimens that were spiked with type-specific antigen, group-specific antigen, or type III organisms. There were sensitivity differences between the assays, but the Bactigen assay performed best, detecting as little as 1 ng of GBS group-specific antigen per ml in urine and as few as 10(5) CFU of GBS type III organisms per ml in urine, serum, and cerebrospinal fluid.
摘要
通过乳胶颗粒凝集试验（LPA）检测尿液中的B族链球菌（GBS）抗原可能有助于快速诊断GBS败血症。我们试图将三种商用LPA检测方法与添加了型特异性抗原、群特异性抗原或III型菌株的标本进行比较。各检测方法之间存在敏感性差异，但Bactigen检测方法表现最佳，能检测出尿液中低至每毫升1纳克的GBS群特异性抗原，以及尿液、血清和脑脊液中低至每毫升10⁵CFU的GBS III型菌株。
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