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[抗生素疗法在慢性阻塞性肺疾病急性加重期的作用]

[Role of antibiotherapy in acute exacerbation of chronic obstructive pulmonary disease].

作者信息

Cavassini M, Calandra T, Bridevaux P O

机构信息

Service des maladies infectieuses, Département de médecine, CHUV, 101I Lausanne.

出版信息

Rev Med Suisse. 2007 Apr 11;3(106):939-42.

Abstract

Two thirds of the exacerbations of chronic obstructive pulmonary disease (COPD) are caused by infections of the respiratory tract. The causative microorganisms differ according to the degree of COPD severity, previous antibiotic therapy and prior bacterial infections. Antibiotics and intensification of bronchodilator therapy are the cornerstones of the management of moderate and severe exacerbations of COPD. Prompt therapy of COPD exacerbations has been shown to reduce the likelihood of hospitalisation and improve the quality of life. In this article, we have reviewed current recommendations regarding the use of antibiotics in the treatment of COPD exacerbations.

摘要

慢性阻塞性肺疾病(COPD)急性加重的三分之二是由呼吸道感染引起的。致病微生物因COPD严重程度、既往抗生素治疗情况及先前细菌感染情况而异。抗生素和强化支气管扩张剂治疗是COPD中重度急性加重管理的基石。已证明对COPD急性加重进行及时治疗可降低住院可能性并改善生活质量。在本文中,我们回顾了目前关于使用抗生素治疗COPD急性加重的建议。

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