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评估两份用于确定金属工人中皮炎情况及其与接触金属加工液之间关系的自填式问卷。

Evaluation of 2 self-administered questionnaires to ascertain dermatitis among metal workers and its relation with exposure to metalworking fluids.

作者信息

de Joode Berna van Wendel, Vermeulen Roel, Heederik Dick, van Ginkel Kees, Kromhout Hans

机构信息

Risk Assessment in the Work Environment, TNO Quality of Life and IRAS Utrecht University, 3508 TD Utrecht, The Netherlands.

出版信息

Contact Dermatitis. 2007 Jun;56(6):311-7. doi: 10.1111/j.1600-0536.2007.01111.x.

Abstract

We performed an exploratory study to evaluate 2 self-administered questionnaires assessing hand dermatitis and investigate a possible exposure-response relationship between dermal exposure to semi-synthetic metalworking fluids (SMWF) and dermatitis. In a cross-sectional survey on dermatitis, a symptom-based questionnaire and a picture-based skin screening list were applied in 80 SMWF-exposed workers and 67 referents. To evaluate the accuracy of the questionnaires, 47 subjects were examined by a dermatologist. Dermal exposure levels to SMWF were assessed on hands, forearms, and face with a observational method that was validated using a fluorescent tracer method. The symptom-based questionnaire had a relatively high sensitivity (0.86) but moderate specificity (0.64), and the skin screening list had a low sensitivity (0.36) and a relatively high specificity (0.84). The skin screening list seemed to represent the more severe cases of dermatitis and showed a significant relation with exposure for dermatitis on hands, forearms, or face. In epidemiological surveys where workers are not seen by a dermatologist, the skin screening list seems to be more appropriate to detect cases of dermatitis, as its higher specificity results in less false positives. Alternatively, it would be preferable applying the symptom-based questionnaire; workers with symptoms should be seen by a dermatologist to identify false positives.

摘要

我们开展了一项探索性研究,以评估两份用于评估手部皮炎的自填式问卷,并调查皮肤接触半合成金属加工液(SMWF)与皮炎之间可能存在的暴露-反应关系。在一项关于皮炎的横断面调查中,对80名接触SMWF的工人和67名对照者应用了基于症状的问卷和基于图片的皮肤筛查清单。为评估问卷的准确性,由一名皮肤科医生对47名受试者进行了检查。采用一种经荧光示踪剂方法验证的观察法评估手部、前臂和面部的SMWF皮肤暴露水平。基于症状的问卷具有相对较高的敏感性(0.86)但特异性中等(0.64),而皮肤筛查清单的敏感性较低(0.36)且特异性相对较高(0.84)。皮肤筛查清单似乎代表了更严重的皮炎病例,并且显示出与手部、前臂或面部皮炎的暴露存在显著关联。在未由皮肤科医生诊治工人的流行病学调查中,皮肤筛查清单似乎更适合用于检测皮炎病例,因为其较高的特异性导致假阳性较少。或者,如果应用基于症状的问卷会更好;有症状的工人应由皮肤科医生诊治以识别假阳性。

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