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[阿根廷共和国真菌病的流行病学状况]

[Epidemiological status of mycoses in the Argentine Republic].

作者信息

Davel G, Canteros C E

机构信息

Departamento Micología, INEI ANLIS "Dr. Carlos G. Malbrán" Avda. Vélez Sarsfield 563 (C1281AFF) Ciudad Autónoma de Buenos Aires, Argentina.

出版信息

Rev Argent Microbiol. 2007 Jan-Mar;39(1):28-33.

PMID:17585656
Abstract

We herein report the results of a retrospective nationwide survey on mycoses diagnosed between January and December, 2004. The study included data provided by 72 laboratories located in 19 provinces and in Buenos Aires City. Out of 801,805 microbiological specimens processed that year, only 62,681 (8%) were submitted to mycological studies. A total of 23,600 mycoses cases were diagnosed: 11,107 (47%) superficial mycoses, 10,830 (46%) mucosal candidiasis and 1,663 (7%) deep mycoses. Relative frequencies of superficial mycoses did not differ significantly (p > 0.05) from frequencies observed in a previous study covering Buenos Aires City and Province (1993), and from two countrywide surveys conducted by the National Network of Mycology Laboratories and National Quality Control Program (NNML and NQCP) in 1999 and 2002. The most frequent deep mycoses were yeast fungaemia (34%), cryptococcosis (20%), broncho-pulmonary aspergillosis (13%), histoplasmosis (11%), paracoccidioidomycosis (7%) and pneumocystosis (5%). In contrast with results of four previous nationwide studies on broncho-pulmonary mycoses including a survey performed by NNML and NQCP in 2002, our study revealed that histoplasmosis prevailed over paracoccidioidomycosis, thus ranking for the first time as the most frequent endemic mycosis in Argentina.

摘要

我们在此报告一项关于2004年1月至12月间诊断的真菌病的全国性回顾性调查结果。该研究纳入了位于19个省和布宜诺斯艾利斯市的72个实验室提供的数据。在当年处理的801,805份微生物标本中,仅有62,681份(8%)进行了真菌学研究。共诊断出23,600例真菌病病例:11,107例(47%)为浅表真菌病,10,830例(46%)为黏膜念珠菌病,1,663例(7%)为深部真菌病。浅表真菌病的相对频率与之前一项涵盖布宜诺斯艾利斯市和省(1993年)的研究以及1999年和2002年由国家真菌学实验室网络和国家质量控制项目(NNML和NQCP)进行的两项全国性调查中观察到的频率相比,差异无统计学意义(p>0.05)。最常见的深部真菌病为酵母菌血症(34%)、隐球菌病(20%)、支气管肺曲霉病(13%)、组织胞浆菌病(11%)、副球孢子菌病(7%)和肺孢子菌病(5%)。与之前四项关于支气管肺真菌病的全国性研究结果(包括NNML和NQCP在2002年进行的一项调查)相比,我们的研究显示组织胞浆菌病的发病率高于副球孢子菌病,因此首次成为阿根廷最常见的地方性真菌病。

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