Bennett Paul, Phelps Ceri, Brain Kate, Hood Kerenza, Gray Jonathon
Nursing, Health and Social Care Research Centre, School of Nursing and Midwifery Studies, Cardiff University, Cardiff, United Kingdom.
J Psychosom Res. 2007 Jul;63(1):59-64. doi: 10.1016/j.jpsychores.2007.01.016.
The aim of this study was to evaluate the effectiveness of a distraction-based coping leaflet in reducing distress in women undergoing genetic risk assessment for breast/ovarian cancer.
One hundred sixty-two women participated in a randomized controlled trial, receiving either the intervention or standard information. Data were collected through a postal questionnaire at entry into a genetic risk assessment programme and 1 month later.
Analysis of covariance revealed a nonsignificant reduction in distress in all women, and a significant reduction of distress among those with high baseline stress, who received the intervention. No gains were found among the control group. Measures of emotional response while thinking about cancer genetic assessment suggested these benefits were achieved in the absence of any rebound emotional response.
The intervention offers a low-cost effective coping intervention, which could be integrated into existing services with minimal disruption and may also be appropriate for other periods of waiting and uncertainty.
本研究旨在评估一份基于分心应对的宣传册在减轻接受乳腺癌/卵巢癌遗传风险评估的女性的痛苦方面的有效性。
162名女性参与了一项随机对照试验，她们被随机分配接受干预措施或标准信息。在进入遗传风险评估项目时以及1个月后，通过邮寄问卷收集数据。
协方差分析显示，所有女性的痛苦程度均有不显著的降低，而基线压力较高且接受干预措施的女性的痛苦程度有显著降低。对照组未发现有改善。在思考癌症遗传评估时的情绪反应测量表明，这些益处是在没有任何情绪反弹的情况下实现的。
该干预措施提供了一种低成本且有效的应对干预方法，可在对现有服务造成最小干扰的情况下融入其中，并且可能也适用于其他等待和不确定时期。
