Hahm Tae-Soo, Lee Jeong-Jin, Yang Mi-Kyung, Kim Jie-Ae
Department of Anesthesiology and Pain Medicine, Samsung Medical Center, 50 Ilwon-dong, Kangnam-gu, Seoul 135-710, Korea.
Yonsei Med J. 2007 Jun 30;48(3):474-9. doi: 10.3349/ymj.2007.48.3.474.
Arrhythmias after an esophagectomy (most commonly atrial fibrillation) are a significant contributing factor to patient morbidity. However, the significance of an intraoperative arrhythmia is not completely understood. The aim of this retrospective study was to determine the occurrence and risk factors for developing intraoperative arrhythmias in patients undergoing an esophagectomy.
We reviewed the records of 427 patients who underwent a transthoracic esophagectomy between 2001 and 2005. Variables such as age, sex, hypertension, diabetes, cardiac disease, preoperative pulmonary function test (PFT) results, cancer level, combined radiochemotherapy, intrathoracic cavity adhesions and anastomosis site, hemoglobin, central venous pressure (CVP), fluid balance, serum potassium level, dose of vasopressors, temperature, and combined general and epidural anesthesia were analyzed as risk factors for the occurrence of an arrhythmia. We defined this arrhythmia as one not originating from the sinus node.
The incidence of intraoperative arrhythmia in this subset of patients was 17.1%, with a 37.2% reoccurrence rate during the first three postoperative days. Univariate and multivariate analysis revealed the presence of heart disease, poor PFTs, cervical anastomosis, elevated CVP, and higher ephedrine doses to be independent predictors of the development of an intraoperative arrhythmia.
The incidence of intraoperative arrhythmia during esophagectomy was 17.1% with a 37.2% of reoccurrence rate.
食管切除术后的心律失常(最常见的是心房颤动)是导致患者发病的一个重要因素。然而,术中心律失常的意义尚未完全明确。这项回顾性研究的目的是确定接受食管切除术患者术中发生心律失常的情况及危险因素。
我们回顾了2001年至2005年间接受经胸食管切除术的427例患者的记录。分析了年龄、性别、高血压、糖尿病、心脏病、术前肺功能测试(PFT)结果、癌症分期、联合放化疗、胸腔粘连和吻合部位、血红蛋白、中心静脉压(CVP)、液体平衡、血清钾水平、血管升压药剂量、体温以及全身麻醉与硬膜外麻醉联合使用等变量,将其作为心律失常发生的危险因素。我们将这种心律失常定义为并非起源于窦房结的心律失常。
该组患者术中心律失常的发生率为17.1%,术后前三天复发率为37.2%。单因素和多因素分析显示,存在心脏病、PFT结果不佳、颈部吻合、CVP升高以及麻黄碱剂量较高是术中发生心律失常的独立预测因素。
食管切除术中术中心律失常的发生率为17.1%,复发率为37.2%。