Colwell Elizabeth M, Encarnacion Carlos O, Rein Lisa E, Szabo Aniko, Haasler George, Gasparri Mario, Tisol William, Johnstone David
Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr. Falk Cardiovascular Research Bldg, Stanford, CA, 94305-5407, USA.
University of Maryland, Division of Cardiac Surgery, 110 S. Paca St. 7th floor, Baltimore, MD, 21201, USA.
J Cardiothorac Surg. 2018 Jun 19;13(1):73. doi: 10.1186/s13019-018-0746-1.
There have been numerous studies regarding atrial fibrillation (AF) associated with cardiac and pulmonary surgery; however, studies looking at esophagectomy and atrial fibrillation are sparse. The goal of this study was to review our institution's atrial fibrillation rate following esophagectomy in order to better define the incidence and predisposing factors in this patient population.
A retrospective chart review of all patients undergoing esophagectomy with transcervical endoscopic mobilization of the esophagus (TEEM) at the Medical College of Wisconsin and Affiliated Hospitals from July 2009 through December 2012.
Seventy-one patients underwent TEEM esophagectomy during the study period. Of those, 23 (32.4%) patients developed new atrial fibrillation postoperatively. ICU (Intensive Care Unit) length of stay was 7.1 days for those that did not receive amiodarone, compared to 5.3 days for those that did receive amiodarone (p < 0.025). Those that went into AF spent on average 9.3 days in the ICU compared to 4.7 days for their counterparts that did not go into AF (p < 0.006). Total length of stay was not statistically different between populations [15.1 +/- 11.3 days compared to 13.5 +/- 9.4 days for those who did not go into AF (p < 0.281)]. Receiving preoperative amiodarone was found to reduce the overall incidence of AF. There was a trend towards decreased risk of going into AF in those who received preoperative amiodarone with an adjusted hazard ratio of 0.555 (p = 0.057).
Similar to data reported in previous literature, postoperative atrial fibrillation was found to increase ICU length of stay as well as overall length of hospital stay. Preoperative amiodarone administration displayed a trend toward decreasing the rates of atrial fibrillation in patients undergoing TEEM.
关于心脏和肺部手术相关的心房颤动(AF)已有大量研究;然而,针对食管切除术与心房颤动的研究却很稀少。本研究的目的是回顾我院食管切除术后的心房颤动发生率,以便更好地明确该患者群体中的发病率及易感因素。
对2009年7月至2012年12月在威斯康星医学院及其附属医院接受经颈部内镜下食管游离术(TEEM)的食管切除术患者进行回顾性病历审查。
在研究期间,71例患者接受了TEEM食管切除术。其中,23例(32.4%)患者术后出现新发心房颤动。未接受胺碘酮治疗的患者重症监护病房(ICU)住院时间为7.1天,而接受胺碘酮治疗的患者为5.3天(p<0.025)。发生心房颤动的患者在ICU平均住院9.3天,未发生心房颤动的患者为4.7天(p<0.006)。两组患者的总住院时间无统计学差异[未发生心房颤动的患者为15.1±11.3天,发生心房颤动的患者为13.5±9.4天(p<0.281)]。术前使用胺碘酮可降低心房颤动的总体发生率。术前使用胺碘酮的患者发生心房颤动的风险有降低趋势,校正风险比为0.555(p = 0.057)。
与既往文献报道的数据相似,术后心房颤动会增加ICU住院时间及总体住院时间。术前给予胺碘酮有降低接受TEEM手术患者心房颤动发生率的趋势。