使用来自加纳急性腹泻儿童粪便样本的轮状病毒和腺病毒免疫层析检测的现场评估。
Field evaluation of a rota- and adenovirus immunochromatographic assay using stool samples from children with acute diarrhea in Ghana.
作者信息
Weitzel Thomas, Reither Klaus, Mockenhaupt Frank P, Stark Klaus, Ignatius Ralf, Saad Eiman, Seidu-Korkor Andrew, Bienzle Ulrich, Schreier Eckart
机构信息
Institute of Tropical Medicine and International Health, Charité, University Medicine Berlin, Spandauer Damm 130, D-14050 Berlin, Germany.
出版信息
J Clin Microbiol. 2007 Aug;45(8):2695-7. doi: 10.1128/JCM.00562-07. Epub 2007 Jun 27.
Abstract
We evaluated the Rida Quick rotavirus/adenovirus Combi rapid immunochromatographic test (ICT) under field conditions with Ghanaian children with acute diarrhea. Compared to PCR results, sensitivities and specificities were 75% and 95% for rotavirus and 22% and 84% for adenovirus. In resource-poor settings, ICTs may help to overcome difficulties in the diagnosis of rotavirus infection.
摘要
我们在加纳患有急性腹泻的儿童中，在现场条件下评估了Rida Quick轮状病毒/腺病毒联合快速免疫层析试验（ICT）。与聚合酶链反应（PCR）结果相比，轮状病毒的敏感性和特异性分别为75%和95%，腺病毒的敏感性和特异性分别为22%和84%。在资源匮乏的环境中，免疫层析试验可能有助于克服轮状病毒感染诊断中的困难。
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