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[从鼠浆细胞瘤MOPC 173中筛选对环磷酸腺苷和茶碱耐药的细胞系。对哇巴因和刀豆球蛋白A的交叉耐药性]

[Selection of cell lines resistant to cyclic AMP and theophylline from murine plasmocytoma MOPC 173. Cross resistance to ouabain and concanavalin A].

作者信息

Paraf A, Faivre E, Zilberfarb V, Lelièvre L, Zachowski A

出版信息

C R Acad Hebd Seances Acad Sci D. 1975 Sep 8;281(10):683-5.

PMID:175967
Abstract

Using cAMP or theophyllin as selective agents, we obtained from contact inhibited and non contact inhibited cell lines, derived from the same plasmocytoma, different resistant cell lines. All of them were cAMP and theophyllin resistant and also ouabain and con A resistant as judged by the growth curves in presence of the different drugs.

摘要

使用环磷酸腺苷(cAMP)或茶碱作为选择剂,我们从源自同一浆细胞瘤的接触抑制和非接触抑制细胞系中获得了不同的抗性细胞系。根据在不同药物存在下的生长曲线判断,所有这些细胞系均对cAMP和茶碱具有抗性,并且对哇巴因和刀豆球蛋白A也具有抗性。

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