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[从小鼠浆细胞瘤MOPC 173中筛选对哇巴因耐药的细胞系。对环磷酸腺苷、茶碱和刀豆球蛋白A的交叉耐药性]

[Selection of cell lines resistant to ouabain from murine plasmacytoma MOPC 173. Cross resistance to cyclic AMP, theophylline, and concanavalin A].

作者信息

Paraf A, Faivre E, Zilberfarb V, Zachowski A, Lelièvre L

出版信息

C R Acad Hebd Seances Acad Sci D. 1975 Sep 1;281(9):567-70.

PMID:174830
Abstract

Using ouabain as a selective agent, we obtained from a contact inhibited and a non contact inhibited cell layer derived from the same plasmocytoma, different resistant cell lines. All of them were ouabain resistant but were also able to grow in presence of normallly toxic levels of cAMP, theophylline and concanavalin A.

摘要

使用哇巴因作为选择剂,我们从源自同一浆细胞瘤的接触抑制和非接触抑制细胞层中获得了不同的抗性细胞系。它们都对哇巴因具有抗性,但也能够在正常毒性水平的环磷酸腺苷(cAMP)、茶碱和伴刀豆球蛋白A存在的情况下生长。

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