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Cancer promotion in a mouse-skin model by a 60-Hz magnetic field: I. Experimental design and exposure system.

作者信息

Stuchly M A, Lecuyer D W, McLean J

机构信息

Bureau of Radiation and Medical Devices, Health & Welfare Canada, Ottawa, Ontario.

出版信息

Bioelectromagnetics. 1991;12(5):261-71. doi: 10.1002/bem.2250120502.

DOI:10.1002/bem.2250120502
PMID:1759977
Abstract

The rationale for selection of an animal model, the experimental design, and the design and evaluation of an exposure system used in studies of 60-Hz magnetic fields are described. The studies were conceived to assay development of cancer and immune responsiveness in mice exposed to magnetic fields. The exposure system utilized a quadrupole-coil configuration to minimize stray magnetic fields. Four square-wound coil provided a uniform field within a volume occupied by 16 animal cages. The magnetic field had a mean flux density of 2 mT that varied less than +/- 10% within the volume occupied by animals' cages. The flux density decreased to less than 0.1 microT at a distance of 2 m from the coils. In each exposure system 32 animals could be housed in plastic cages.

摘要

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