Foglia G, Sateren W B, Renzullo P O, Bautista C T, Langat L, Wasunna M K, Singer D E, Scott P T, Robb M L, Birx D L
U.S. Army Medical Research Unit-Kenya, Nairobi, Kenya.
Epidemiol Infect. 2008 May;136(5):694-702. doi: 10.1017/S0950268807009028. Epub 2007 Jun 29.
Human immunodeficiency virus type 1 (HIV-1) epidemiology among residents of a rural agricultural plantation in Kericho, Kenya was studied. HIV-1 prevalence was 14.3%, and was higher among women (19.1%) than men (11.3%). Risk factors associated with HIV-1 for men were age (>or=25 years), marital history (one or more marriages), age difference from current spouse (>or=5 years), Luo ethnicity, sexually transmitted infection (STI) symptoms in the past 6 months, circumcision (protective), and sexual activity (>or=7 years). Among women, risk factors associated with HIV-1 were age (25-29 years, >or=35 years), marital history (one or more marriages), age difference from current spouse (>or=10 years), Luo ethnicity, STI symptoms in the past 6 months, and a STI history in the past 5 years. Most participants (96%) expressed a willingness to participate in a future HIV vaccine study. These findings will facilitate targeted intervention and prevention measures for HIV-1 infection in Kericho.
对肯尼亚克里乔一个乡村农业种植园居民中的1型人类免疫缺陷病毒（HIV-1）流行病学情况进行了研究。HIV-1感染率为14.3%，女性（19.1%）高于男性（11.3%）。男性与HIV-1相关的危险因素包括年龄（≥25岁）、婚姻史（一次或多次婚姻）、与现任配偶的年龄差（≥5岁）、卢奥族裔、过去6个月内有性传播感染（STI）症状、包皮环切术（有保护作用）以及性活动（≥7年）。在女性中，与HIV-1相关的危险因素包括年龄（25 - 29岁、≥35岁）、婚姻史（一次或多次婚姻）、与现任配偶的年龄差（≥10岁）、卢奥族裔、过去6个月内有STI症状以及过去5年内有STI病史。大多数参与者（96%）表示愿意参加未来的HIV疫苗研究。这些研究结果将有助于在克里乔针对HIV-1感染采取有针对性的干预和预防措施。
