Li Yong-Jie, Ga Sa-Na, Huo Yang, Li Shao-Ying, Gao Xu-Guang
Department of Neurology, Peking University People's Hospital, Beijing, China.
Neurol Res. 2007 Dec;29(8):803-6. doi: 10.1179/016164107X223557.
BACKGROUND/OBJECTIVES: The volume of hippocampus has been associated with a number of disorders and would be helpful in clinical and research practice. This study provided the normal data of hippocampal volumes in a healthy Chinese sample and assessed the possible effects of age, gender and side on it.
Sixty-one normal participants with a broad age span from 6 to 82 years were enrolled in the study. The hippocampal volumes of them were obtained from oblique coronal MR images using inversion recovery (IR) sequence and normalized to adjust intersubject variation in head size.
The corrected volume in the right side of hippocampus was 2.204-2.944 cm(3), and 2.068-2.700 cm(3) in the left. There were no statistically significant differences among different age and gender groups (p>0.05). The volume of right hippocampus was larger than that of the left side (p<0.001).
We presented the volume range of hippocampus in healthy Chinese on MRI in this study. No age and gender effects were found on hippocampal volumes. Side-to-side asymmetry was obtained by statistical analysis.
背景/目的：海马体的体积与多种疾病相关，对临床和研究实践有帮助。本研究提供了健康中国人群样本中海马体体积的正常数据，并评估了年龄、性别和左右侧对其可能产生的影响。
61名年龄范围从6岁到82岁的正常参与者被纳入研究。使用反转恢复（IR）序列从斜冠状面磁共振图像中获取他们的海马体体积，并进行标准化以调整个体间头部大小的差异。
右侧海马体的校正体积为2.204 - 2.944立方厘米，左侧为2.068 - 2.700立方厘米。不同年龄和性别组之间无统计学显著差异（p>0.05）。右侧海马体的体积大于左侧（p<0.001）。
本研究展示了健康中国人海马体在磁共振成像上的体积范围。未发现年龄和性别对海马体体积有影响。通过统计分析得出了左右侧不对称性。
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