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颞叶前部和海马结构:年轻成年人磁共振图像的正常体积测量

Anterior temporal lobes and hippocampal formations: normative volumetric measurements from MR images in young adults.

作者信息

Jack C R, Twomey C K, Zinsmeister A R, Sharbrough F W, Petersen R C, Cascino G D

机构信息

Department of Diagnostic Radiology, Mayo Clinic, Rochester, MN 55905.

出版信息

Radiology. 1989 Aug;172(2):549-54. doi: 10.1148/radiology.172.2.2748838.

DOI:10.1148/radiology.172.2.2748838
PMID:2748838
Abstract

Volumes of the right and left anterior temporal lobes and hippocampal formations were measured from magnetic resonance images in 52 healthy volunteers, aged 20-40 years. Subjects were selected by age, sex, and handedness to evaluate possible effect of these variables. Data were normalized for variation in total intracranial volume between individuals. Right-left asymmetry in the volumes of the anterior temporal lobes and hippocampal formations was a normal finding. The anterior temporal lobe of the non-dominant (right) hemisphere was larger than the left by a small (mean right-left difference, 2.3 cm3) but statistically significant amount (P less than .005) in right-handed subjects. No significant effect of age or sex was seen in normalized right or left anterior temporal lobe volume. The right hippocampal formation was larger than the left for all subjects by a small (mean right-left difference, 0.3 cm3) but statistically significant amount (P less than .001). No effect of age, sex, or handedness was seen in normalized hippocampal formation volumes.

摘要

对52名年龄在20至40岁之间的健康志愿者的磁共振图像测量了左右前颞叶和海马结构的体积。根据年龄、性别和利手选择受试者,以评估这些变量可能产生的影响。对个体间总颅内体积的差异进行数据标准化处理。前颞叶和海马结构体积的左右不对称是正常现象。在右利手受试者中,非优势(右)半球的前颞叶比左侧大,差异较小(左右平均差异为2.3立方厘米),但具有统计学意义(P小于0.005)。在标准化的左右前颞叶体积中,未发现年龄或性别的显著影响。所有受试者的右侧海马结构均比左侧大,差异较小(左右平均差异为0.3立方厘米),但具有统计学意义(P小于0.001)。在标准化的海马结构体积中,未发现年龄、性别或利手的影响。

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