Waite Aaron, Faulkner Nathan, Olson Randall J
Department of Ophthalmology and Visual Sciences, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Am J Ophthalmol. 2007 Jul;144(1):143-4. doi: 10.1016/j.ajo.2007.03.015.
To study glistenings in single-piece AcrySof (models SA60 and SN60; Alcon, Fort Worth, Texas, USA) intraocular lenses (IOLs).
Observational, longitudinal study.
Consecutive patients with the SA60 were examined at 12, 24, and 36 months after surgery; those with the SN60 were examined 12 months after surgery. Best-corrected logarithm of the minimum angle of resolution visual acuity, glare testing, contrast sensitivity, and wavefront analysis were performed. Any patient with pathologic features likely to impact visual quality was eliminated. All IOLs were photographed, and glistenings were analyzed for size and density by a computer program.
All IOLs had glistenings, and neither size, density, nor severity index (size x density) correlated with acuity, glare testing, or wavefront analysis results. High spatial resolution contrast acuity (patch D) had a borderline correlation (P = .06) with severity index, as did progress over time (P = .04).
All IOLs studied had glistenings. High spatial resolution contrast sensitivity impact and severity progression over time deserve further study.
研究单片式AcrySof（型号SA60和SN60；美国德克萨斯州沃思堡爱尔康公司）人工晶状体（IOL）中的闪光现象。
观察性纵向研究。
对接受SA60型号人工晶状体植入手术的患者在术后12、24和36个月进行检查；对接受SN60型号人工晶状体植入手术的患者在术后12个月进行检查。进行最佳矫正最小分辨角对数视力、眩光测试、对比敏感度和波前分析。排除任何具有可能影响视觉质量的病理特征的患者。对所有人工晶状体进行拍照，并通过计算机程序分析闪光的大小和密度。
所有人工晶状体均出现闪光现象，且闪光的大小、密度或严重程度指数（大小×密度）与视力、眩光测试或波前分析结果均无相关性。高空间分辨率对比敏感度（斑块D）与严重程度指数存在边缘相关性（P = 0.06），随时间的进展情况也与之相关（P = 0.04）。
所研究的所有人工晶状体均出现闪光现象。高空间分辨率对比敏感度的影响以及随时间的严重程度进展值得进一步研究。
