Dhaliwal D K, Mamalis N, Olson R J, Crandall A S, Zimmerman P, Alldredge O C, Durcan F J, Omar O
John Moran Eye Center, Department of Ophthalmology, University of Utah, Salt Lake City, USA.
J Cataract Refract Surg. 1996 May;22(4):452-7. doi: 10.1016/s0886-3350(96)80041-1.
To investigate the visual significance of "glistenings" in acrylic intraocular lenses (IOLS).
John Moran Eye Center, University of Utah, Salt Lake City.
Seventeen patients who had phacoemulsification with implantation of the AcrySof acrylic IOL were evaluated by slitlamp examination and visual acuity, contrast sensitivity, and glare testing. Ten patients had a silicone posterior chamber IOL in the opposite eye and had testing with similar visual parameters for comparison. Glistenings noted in the acrylic IOLs were graded at the slitlamp. Laboratory analysis of five acrylic IOLs was also done to reproduce the glistenings noted clinically.
All 17 patients with the acrylic IOLs had some lenticular glistenings, ranging from trace to 2+. Statistical analysis of visual acuity, contrast sensitivity, and glare testing revealed a statistically significant difference between the acrylic and the silicone IOLs only in contrast sensitivity. Laboratory analysis of the acrylic IOLs showed similar glistenings from 48 to 72 hours after they were placed in balanced salt solution.
A patients who received AcrySof IOLs that came in the AcryPak had some degree of glistenings. There was also a significant decrease in contrast sensitivity compared with that of fellow eyes with silicone IOLs. The glistenings are likely caused by water vacuoles that form within the lens after hydration within the eyes. Further studies are necessary to assess the exact cause of these glistenings.
研究丙烯酸人工晶状体（IOL）中“闪光”的视觉意义。
犹他大学约翰·莫兰眼科中心，盐湖城。
对17例行超声乳化并植入AcrySof丙烯酸IOL的患者进行裂隙灯检查、视力、对比敏感度和眩光测试评估。10例患者对侧眼植入了硅酮后房型IOL，并进行了类似视觉参数的测试以作比较。在裂隙灯下对丙烯酸IOL中观察到的闪光进行分级。还对5个丙烯酸IOL进行了实验室分析，以重现临床观察到的闪光现象。
所有17例植入丙烯酸IOL的患者均有一些晶状体闪光，范围从微量到2+。视力、对比敏感度和眩光测试的统计分析显示，仅在对比敏感度方面，丙烯酸IOL和硅酮IOL之间存在统计学上的显著差异。丙烯酸IOL的实验室分析表明，将其置于平衡盐溶液中48至72小时后会出现类似的闪光现象。
接受AcryPak包装的AcrySof IOL的患者有一定程度的闪光现象。与植入硅酮IOL的对侧眼相比，对比敏感度也有显著下降。闪光可能是由于眼内水化后晶状体内部形成的水空泡所致。需要进一步研究以评估这些闪光的确切原因。
