Warady Bradley A, Jennings Janelle
Children's Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA.
Perit Dial Int. 2007 Jul-Aug;27(4):441-5.
The peritoneal equilibration test (PET) is a 4-hour procedure that is recommended to be performed in children receiving peritoneal dialysis to assist in prescription management. While a shortened version of the PET has been used in adults and reliably characterizes peritoneal membrane transport capacity, no similar experience with children has been reported.
Retrospective evaluation of 2-hour and 4-hour PET data obtained from 20 children receiving chronic peritoneal dialysis in a single center. Characterization of membrane transport capacity was based on evaluation of serum and dialysate samples used to determine the dialysate-to-plasma ratio (D/P) of creatinine and the ratio of dialysate glucose to baseline dialysate glucose (D/D(0)). Patient values were compared to pediatric reference data.
In all 20 patients, characterization of peritoneal membrane transport capacity using 2-hour D/P and D/D(0) results was identical to that determined using 4-hour data for the same solute. While the creatinine- and glucose-based characterization was discrepant in 14 of 20 patients, in only 1 case was the discrepancy of more than a single transport category.
These results support the accuracy of a short PET in children, a procedure that should prove beneficial in terms of patient and staff time.
腹膜平衡试验（PET）是一项需时4小时的检查，推荐用于接受腹膜透析的儿童，以辅助处方管理。虽然PET的缩短版已用于成人，且能可靠地描述腹膜转运能力，但尚无儿童方面的类似经验报道。
回顾性评估在单一中心接受慢性腹膜透析的20名儿童的2小时和4小时PET数据。基于对用于测定肌酐的透析液与血浆比值（D/P）以及透析液葡萄糖与基线透析液葡萄糖比值（D/D(0)）的血清和透析液样本的评估来描述膜转运能力。将患者的值与儿科参考数据进行比较。
在所有20例患者中，使用2小时D/P和D/D(0)结果对腹膜膜转运能力的描述与使用相同溶质的4小时数据所确定的结果相同。虽然在20例患者中有14例基于肌酐和葡萄糖的描述存在差异，但只有1例差异超过一个转运类别。
这些结果支持儿童短PET的准确性，该检查在节省患者和工作人员时间方面应被证明是有益的。
