Arayne M Saeed, Sultana Najma, Mirza Agha Zeeshan, Zuberi M Hashim, Siddiqui Farhan Ahmed
Department of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Pak J Pharm Sci. 2007 Oct;20(4):268-73.
Pakistan is rich in medicinally important plants and has ancient herbal treatment methods. Present work is based on the study of six indigenous plants Eugenia jambolana, Lawsonia inermis, Momordica charantia, Morus alba, Nigella sativa and Trigonella foenum graecum which show the inhibitory effect of glucose utilization, and are in use as hypoglycemic agents of varying degree in traditional system of medicine. The glucose uptake activity of (methanolic extracts) of these plants was tested in vitro and glucose was estimated by glucose oxidase method. The results in three different media revealed that, hypoglycemic activity is more prominent in neutral and basic media as compared to acidic medium.
巴基斯坦拥有丰富的具有药用价值的植物，并拥有古老的草药治疗方法。目前的研究基于对六种本土植物的研究，即蒲桃、散沫花、苦瓜、桑、黑种草和胡芦巴，这些植物显示出对葡萄糖利用的抑制作用，并且在传统医学体系中不同程度地用作降血糖剂。对这些植物（甲醇提取物）的葡萄糖摄取活性进行了体外测试，并通过葡萄糖氧化酶法测定葡萄糖含量。在三种不同培养基中的结果表明，与酸性培养基相比，降血糖活性在中性和碱性培养基中更为显著。
