Templeton Maie, Palazzo Mark G A
Hammersmith Hospitals NHS Trust, Charing Cross Hospital, Division Critical Care Medicine, W6 RF, London, UK.
Intensive Care Med. 2007 Nov;33(11):1938-45. doi: 10.1007/s00134-007-0762-4. Epub 2007 Jul 3.
This study aimed to determine the impact of providing chest physiotherapy after routine clinical assessment on the duration of mechanical ventilation, outcome and intensive care length of stay.
Single-centre, single-blind, prospective, randomised, controlled trial in a university hospital general intensive care unit.
180 patients requiring mechanical ventilation for more than 48 h.
Patients randomly allocated, one group receiving physiotherapy as deemed appropriate by physiotherapists after routine daily assessments and another group acting as controls were limited to receiving decubitus care and tracheal suctioning.
Primary endpoints were initial time to become ventilator-free, secondary endpoints included intensive care unit (ICU) and hospital mortality and ICU length of stay. Kaplan-Meier analysis censored for death revealed a significant prolongation of median time to become ventilator-free among patients receiving physiotherapy (p=0.047). The time taken for 50% of patients (median time) to become ventilator-free was 15 and 11 days, respectively, for physiotherapy and control groups. There were no differences between groups in ICU or hospital mortality rates, or length of ICU stay. The number of patients needing re-ventilation for respiratory reasons was similar in both groups.
本研究旨在确定在常规临床评估后进行胸部物理治疗对机械通气时间、结局及重症监护病房住院时长的影响。
在一所大学医院的综合重症监护病房进行的单中心、单盲、前瞻性、随机对照试验。
180例需要机械通气超过48小时的患者。
患者被随机分配,一组在每日常规评估后接受物理治疗师认为合适的物理治疗,另一组作为对照组,仅限于接受卧位护理和气管吸痰。
主要终点是首次脱离呼吸机的时间,次要终点包括重症监护病房(ICU)和医院死亡率以及ICU住院时长。经死亡截尾的Kaplan-Meier分析显示,接受物理治疗的患者中首次脱离呼吸机的中位时间显著延长(p=0.047)。物理治疗组和对照组中50%的患者(中位时间)分别在15天和11天脱离呼吸机。两组在ICU或医院死亡率以及ICU住院时长方面无差异。两组因呼吸原因需要再次通气的患者数量相似。