Chen Stephen T, Darby Ivan B, Reynolds Eric C
Centre for Oral Health Science, School of Dental Science, The University of Melbourne, Melbourne, Vic., Australia.
Clin Oral Implants Res. 2007 Oct;18(5):552-62. doi: 10.1111/j.1600-0501.2007.01388.x. Epub 2007 Jun 30.
To evaluate healing of marginal defects in immediate transmucosal implants grafted with anorganic bovine bone, and to assess mucosal and radiographic outcomes 3-4 years following restoration.
Thirty immediate transmucosal implants in maxillary anterior extraction sites of 30 patients randomly received BioOss (N=10; BG), BioOss and resorbable collagen membrane (N=10; BG+M) or no graft (N=10; control).
Vertical defect height (VDH) reductions of 81.2+/-5%, 70.5+/-17.4% and 68.2+/-16.6%, and horizontal defect depth (HDD) reductions of 71.7+/-34.3%, 81.7+/-33.7% and 55+/-28.4% were observed for BG, BG+M and control groups, respectively, with no significant inter-group differences. Horizontal resorption was significantly greater in control group (48.3+/-9.5%) when compared with BG (15.8+/-16.9%) and BG+M (20+/-21.9%) groups (P=0.000). Ten sites (33.3%) exhibited recession of the mucosa after 6 months; eight (26.7%) had an unsatisfactory esthetic result post-restoration due to recession. Mucosal recession was significantly associated (P=0.032) with buccally positioned implants (HDD 1.1+/-0.3 mm) when compared with lingually positioned implants (HDD 2.3+/-0.6 mm). In 19 patients followed for a mean of 4.0+/-0.7 years, marginal mucosa and bone levels remained stable following restoration.
BioOss significantly reduced horizontal resorption of buccal bone. There is a risk of mucosal recession and adverse soft tissue esthetics with immediate implant placement. However, this risk may be reduced by avoiding a buccal position of the implant in the extraction socket.
评估即刻经黏膜种植体植入脱蛋白牛骨后边缘缺损的愈合情况,并评估修复后3 - 4年的黏膜及影像学结果。
30例患者上颌前牙拔除位点的30颗即刻经黏膜种植体被随机分为3组,分别植入BioOss(N = 10;BG组)、BioOss和可吸收胶原膜(N = 10;BG + M组)或不植入移植物(N = 10;对照组)。
BG组、BG + M组和对照组的垂直缺损高度(VDH)分别降低了81.2±5%、70.5±17.4%和68.2±16.6%,水平缺损深度(HDD)分别降低了71.7±34.3%、81.7±33.7%和55±28.4%,组间差异无统计学意义。与BG组(15.8±16.9%)和BG + M组(20±21.9%)相比,对照组的水平吸收明显更大(48.3±9.5%)(P = 0.000)。6个月后,10个位点(33.3%)出现黏膜退缩;8个位点(26.7%)修复后美学效果不佳,原因是黏膜退缩。与舌侧植入的种植体(HDD 2.3±0.6 mm)相比,颊侧植入的种植体(HDD 1.1±0.3 mm)黏膜退缩显著相关(P = 0.032)。在平均随访4.0±0.7年的19例患者中,修复后边缘黏膜和骨水平保持稳定。
BioOss显著减少了颊侧骨的水平吸收。即刻种植存在黏膜退缩和软组织美学效果不佳的风险。然而,通过避免种植体在拔牙窝内的颊侧位置,这种风险可能会降低。