Eggspuehler Andreas, Sutter Martin A, Grob Dieter, Porchet F, Jeszenszky Dezsö, Dvorak Jiri
Department of Neurology/Spine Unit, Schulthess Clinic, Lengghalde 2, 8008, Zürich, Switzerland.
Eur Spine J. 2007 Nov;16 Suppl 2(Suppl 2):S216-20. doi: 10.1007/s00586-007-0425-8. Epub 2007 Jul 4.
A prospective study of 36 patients who received multimodal intraoperative monitoring (MIOM) during decompression of thoracic spinal stenosis between March 2000 and December 2005 was chosen as the study design. The objective was to determine the sensitivity and specificity of MIOM techniques used for monitoring spinal cord during surgical thoracic decompression. The background data revealed that the surgical decompression for thoracic spinal stenosis is less frequent than in other regions of the spine. However, due to the relative narrow spinal canal, neurological complications could be severe. The combination of monitoring ascending and descending pathways may provide an early alert to the surgeon in order to alter the surgical procedure, and avoid neurological complications. The methods involved evaluation of intraoperative somatosensory spinal and cerebral evoked potentials and motor evoked potentials of the spinal cord and muscles that were compared with post operative clinical neurological changes. 36 consecutive patients with thoracic spinal stenosis of different aetiologies were monitored by the means of MIOM during the surgical procedure. 31 patients had true negative while one patient had false positive findings. Three patients had true positive and one patient had false negative findings. This indicates a sensitivity of 75% and a specificity of 97%. The one case of false negative findings recovered completely within 3 months. In conclusion, the MIOM is an effective method of monitoring the spinal cord during surgical decompression of the thoracic spine.
选取2000年3月至2005年12月期间36例在胸段脊髓狭窄减压术中接受多模式术中监测(MIOM)的患者进行前瞻性研究作为研究设计。目的是确定在胸段手术减压过程中用于监测脊髓的MIOM技术的敏感性和特异性。背景数据显示,胸段脊髓狭窄的手术减压比脊柱其他部位少见。然而,由于椎管相对狭窄,神经并发症可能很严重。监测上行和下行通路的组合可为外科医生提供早期警报,以便改变手术程序并避免神经并发症。方法包括评估术中脊髓体感和脑诱发电位以及脊髓和肌肉的运动诱发电位,并与术后临床神经学变化进行比较。36例不同病因的胸段脊髓狭窄患者在手术过程中通过MIOM进行监测。31例患者结果为真阴性,1例患者结果为假阳性。3例患者结果为真阳性,1例患者结果为假阴性。这表明敏感性为75%,特异性为97%。1例假阴性结果的患者在3个月内完全康复。总之,MIOM是胸段脊柱手术减压过程中监测脊髓的有效方法。