Ghassemi-Broumand Mohammad, Aslani Jafar, Emadi Seyed-Naser
Department of Optometry, Faculty of Rehabilitation, Shahid Beheshti University (M.C), Tehran, Iran.
Cutan Ocul Toxicol. 2008;27(4):295-305. doi: 10.1080/15569520802327807.
The purpose of our study was to evaluate the late ocular, pulmonary, and cutaneous complications of mustards, 19 years after exposure in 600 patients of the city of Sardasht, Iran. In this case study, we evaluated 600 warfare patients aged 19 to 80 years whose mustard gas injury dated back to 19 years before evaluation in Sardasht. Our results showed that 5.2% of our cases were aged 19-20 years, 18.5% were aged 21-30 years, 31.7% were aged 31-40 years, 23.5% were aged 41-50 years, 12.2% were aged 51-60 years, 5.5% were aged 61-70 years, and 3.4% were aged 71-80 years. There were 50.3% male patients in our study, and 83.2% of the patients were married. Primary ocular manifestations were present in 96.2% of the cases, respiratory manifestations in 80.7%, and cutaneous manifestations in 83.8%, with a hospitalization rate of 64.7%. Ophthalmic, respiratory, and dermal medications were administered in 72.8%, 66.7%, and 61.8% of cases, respectively. The degree of ocular complications was mild in 36.7% and moderate in 1%. Respiratory complications were mild in 45% and moderate in 0.8%. Cutaneous complications were mild in 31.3% and moderate in 0.2.%. Late mild respiratory complications were significantly more frequent than ocular and cutaneous complications. In conclusion, late mild pulmonary complications were more frequent than mild ocular and cutaneous complications; however, moderate ocular complications were more frequent than moderate pulmonary and cutaneous complications.
我们研究的目的是评估伊朗萨尔达什特市600名患者在接触芥子气19年后出现的眼部、肺部和皮肤晚期并发症。在本病例研究中，我们评估了600名年龄在19至80岁之间的战争受害者，他们的芥子气损伤可追溯至在萨尔达什特进行评估前的19年。我们的结果显示，5.2%的病例年龄在19 - 20岁，18.5%年龄在21 - 30岁，31.7%年龄在31 - 40岁，23.5%年龄在41 - 50岁，12.2%年龄在51 - 60岁，5.5%年龄在61 - 70岁，3.4%年龄在71 - 80岁。我们研究中的男性患者占50.3%，83.2%的患者已婚。96.2%的病例有眼部初始表现，80.7%有呼吸系统表现，83.8%有皮肤表现，住院率为64.7%。分别有72.8%、66.7%和61.8%的病例接受了眼科、呼吸科和皮肤科药物治疗。眼部并发症程度为轻度的占36.7%，中度的占1%。呼吸系统并发症轻度的占45%，中度的占0.8%。皮肤并发症轻度的占31.3%，中度的占0.2%。晚期轻度呼吸系统并发症比眼部和皮肤并发症更为常见。总之，晚期轻度肺部并发症比轻度眼部和皮肤并发症更常见；然而，中度眼部并发症比中度肺部和皮肤并发症更常见。
