King Tonya S, Chinchilli Vernon M, Wang Kai-Ling, Carrasco Josep L
Pennsylvania State University College of Medicine, Pennsylvania 17033, USA.
J Biopharm Stat. 2007;17(4):653-72. doi: 10.1080/10543400701329455.
The repeated measures concordance correlation coefficient was proposed for measuring agreement between two raters or two methods of measuring a response in the presence of repeated measurements (King et al., 2007). This paper proposes a class of repeated measures concordance correlation coefficients that are appropriate for both continuous and categorical data. We illustrate the methodology with examples comparing (1) 1-hour vs. 2-hour blood draws for measuring cortisol in an asthma clinical trial, (2) two measurements of percentage body fat, from skinfold calipers and dual energy x-ray absorptiometry, and (3) two binary measures of quality of health from an asthma clinical trial.
重复测量一致性相关系数是为了在存在重复测量的情况下,测量两个评估者之间或两种测量反应的方法之间的一致性而提出的(King等人,2007年)。本文提出了一类适用于连续数据和分类数据的重复测量一致性相关系数。我们通过实例来说明该方法,这些实例比较了:(1)在一项哮喘临床试验中,测量皮质醇时1小时与2小时采血的情况;(2)通过皮褶厚度卡尺和双能X线吸收法对身体脂肪百分比进行的两次测量;以及(3)一项哮喘临床试验中对健康质量的两种二元测量。