Cofrancesco Joseph, Brown Todd T, Luo Robert F, John Majnu, Stewart Kerry J, Dobs Adrian S
Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.
Am J Drug Alcohol Abuse. 2007;33(3):467-74. doi: 10.1080/00952990701301616.
This cross-sectional study of adult (137 male, 128 female), urban, community dwelling users and nonusers of illicit drugs evaluated associations of demographic, medical, and drug factors with body composition. The population was 49% HIV-positive and 94% African-American. In multivariate analysis, there were no body composition differences among males based on drug use. Among females, the highest tertile of drug use had less fat (12.3 vs.19.9 kg, p = .01) and lower body mass index (21.9 vs. 25.1, p = .01) versus less frequent or nonusers. These data suggest a sex difference in body composition associated with drug use.
这项横断面研究对城市社区中成年非法药物使用者和非使用者(137名男性,128名女性)进行了评估,以探究人口统计学、医学和药物因素与身体成分之间的关联。该人群中49%为HIV阳性,94%为非裔美国人。在多变量分析中,基于药物使用情况,男性的身体成分没有差异。在女性中,与使用频率较低或不使用药物的女性相比,药物使用量最高的三分位数组脂肪更少(12.3千克对19.9千克,p = 0.01),体重指数更低(21.9对25.1,p = 0.01)。这些数据表明,与药物使用相关的身体成分存在性别差异。