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社会支持在帕金森病抑郁中起作用:一项中国队列的横断面研究

Social support plays a role in depression in Parkinson's disease: a cross-section study in a Chinese cohort.

作者信息

Cheng Yanbo, Liu Chunfeng, Mao Chengjie, Qian Jinjun, Liu Kangyong, Ke Guoxiu

机构信息

Department of Neurology, Second Affiliated Hospital of Soochow University, Suzhou, China.

出版信息

Parkinsonism Relat Disord. 2008;14(1):43-5. doi: 10.1016/j.parkreldis.2007.05.011. Epub 2007 Jul 9.

Abstract

To investigate the association between social support and depression in Parkinson's disease (PD), 121 PD patients were enrolled in our study. Interview of questionnaires and neurological examinations, including Hamilton Depression Rating Scale, Chinese Social Support Rating Scale (SSRS), Hoehn and Yahr Stage, Schwab and England Scale (SE) and unified PD Rating Scale (UPDRS) were performed. Increased level of UPDRS and lowered social support were associated with depression in PD patients. Stepwise regression analysis showed that objective social support, UPDRS part 1 and duration of disease manifested significant correlation to patients' depression degree. Therefore, social support plays an important role in depression in PD.

摘要

为研究帕金森病(PD)患者社会支持与抑郁之间的关联,我们招募了121例PD患者。进行了问卷调查访谈以及神经学检查,包括汉密尔顿抑郁量表、中国社会支持评定量表(SSRS)、 Hoehn和Yahr分期、Schwab和England量表(SE)以及统一帕金森病评定量表(UPDRS)。PD患者中,UPDRS水平升高和社会支持降低与抑郁相关。逐步回归分析显示,客观社会支持、UPDRS第1部分及病程与患者抑郁程度显著相关。因此,社会支持在PD患者的抑郁中起重要作用。

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