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本文引用的文献

1
Brugada syndrome: report of the second consensus conference.布加综合征：第二次共识会议报告
Heart Rhythm. 2005 Apr;2(4):429-40. doi: 10.1016/j.hrthm.2005.01.005.
2
Catecholaminergic polymorphic ventricular tachycardia.儿茶酚胺能多形性室性心动过速
Heart Rhythm. 2005 May;2(5):550-4. doi: 10.1016/j.hrthm.2005.01.024.
3
Brugada pattern electrocardiographic changes associated with profound electrolyte disturbance.与严重电解质紊乱相关的Brugada波型心电图改变。
Pacing Clin Electrophysiol. 2004 Jul;27(7):1020-3. doi: 10.1111/j.1540-8159.2004.00579.x.
4
Prevalence of drug-induced electrocardiographic pattern of the Brugada syndrome in a healthy population.健康人群中药物诱导的Brugada综合征心电图模式的患病率。
Am J Cardiol. 2004 Jul 15;94(2):230-3. doi: 10.1016/j.amjcard.2004.03.072.
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Changes in body surface potential distributions induced by isoproterenol and Na channel blockers in patients with the Brugada syndrome.
Int J Cardiol. 2004 Jun;95(2-3):261-8. doi: 10.1016/j.ijcard.2003.05.025.
6
Incidence, clinical implications and prognosis of atrial arrhythmias in Brugada syndrome.Brugada综合征中心房心律失常的发生率、临床意义及预后
Eur Heart J. 2004 May;25(10):879-84. doi: 10.1016/j.ehj.2004.01.004.
7
Prevalence and prognosis of subjects with Brugada-type ECG pattern in a young and middle-aged Finnish population.芬兰中青年人群中出现Brugada型心电图模式者的患病率及预后
Eur Heart J. 2004 May;25(10):874-8. doi: 10.1016/j.ehj.2004.01.011.
8
Determinants of sudden cardiac death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardiac arrest.心电图表现为Brugada综合征且既往无心脏骤停患者心脏性猝死的决定因素
Circulation. 2003 Dec 23;108(25):3092-6. doi: 10.1161/01.CIR.0000104568.13957.4F. Epub 2003 Nov 17.
9
Ventricular arrhythmia induced by sodium channel blocker in patients with Brugada syndrome.布加综合征患者中钠通道阻滞剂诱发的室性心律失常。
J Am Coll Cardiol. 2003 Nov 5;42(9):1624-31. doi: 10.1016/j.jacc.2003.06.004.
10
Autonomic imbalance as a property of symptomatic Brugada syndrome.自主神经失衡作为有症状Brugada综合征的一个特征。
Circ J. 2003 Jun;67(6):511-4. doi: 10.1253/circj.67.511.

抗心律失常药物诱发的 Brugada 综合征电风暴：一例报告

Antiarrhythmic induced electrical storm in Brugada syndrome: a case report.

作者信息

Joshi Sandeep, Raiszadeh Farbod, Pierce Walter, Steinberg Jonathan S

机构信息

Division of Cardiology, St. Luke's-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA.

出版信息

Ann Noninvasive Electrocardiol. 2007 Jul;12(3):274-8. doi: 10.1111/j.1542-474X.2007.00171.x.

DOI:10.1111/j.1542-474X.2007.00171.x
PMID:17617073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6932674/
Abstract

Brugada syndrome (BS) may be "unmasked" by several pharmacological and/or physiological agents in an otherwise normal electrocardiogram. Once diagnosed the possibility of persistent ventricular tachycardia/fibrillation exists. Although this is treated with various antiarrhythmic agents, there remains a cohort of patients who fail to respond to conventional antiarrhythmic therapy therefore, amplifying the electrical storm. We report a case of a BS diagnosed via procainamide challenge, the resultant near fatal electrical storm aggravated by amiodarone and the eventual resolution with isoproterenol.

摘要

Brugada综合征（BS）在原本正常的心电图中可能会被多种药理和/或生理因素“诱发”。一旦确诊，就存在持续性室性心动过速/心室颤动的可能性。尽管使用了各种抗心律失常药物进行治疗，但仍有一部分患者对传统抗心律失常治疗无反应，从而加剧了电风暴。我们报告一例通过普鲁卡因胺激发试验诊断为BS的病例，胺碘酮加重了由此引发的近乎致命的电风暴，而异丙肾上腺素最终使其得到缓解。