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用于估计剂量不确定性的氡气肺部剂量测定模型比较。

Comparison of radon lung dosimetry models for the estimation of dose uncertainties.

作者信息

Winkler-Heil Renate, Hofmann Werner, Marsh James, Birchall Alan

机构信息

Division of Physics and Biophysics, Department of Materials Engineering and Physics, University of Salzburg, Hellbrunner Str. 34, 5020 Salzburg, Austria.

出版信息

Radiat Prot Dosimetry. 2007;127(1-4):27-30. doi: 10.1093/rpd/ncm339. Epub 2007 Jul 9.

Abstract

In order to investigate the degree of dose uncertainty produced by different models, three dosimetry models were compared with each other, representing different classes of models: (i) The RADEP/IMBA model based on the ICRP Human Respiratory Tract Model, a deterministic regional compartment model, (ii) the RADOS model, a deterministic airway generation model and (iii) the IDEAL dosimetry model, a stochastic airway generation model. The outputs of the three models for defined mining exposure conditions were compared at three different levels: deposition fractions for attached and unattached radon progeny; nuclear transformations, reflecting the combined effect of deposition and clearance; and resulting cellular doses. Resulting dose exposure conversion factors ranged from 7.8 (median) mSv/WLM (IDEAL) to 11.8 mSv/WLM (RADEP/IMBA), with 8.3 mSv/WLM (RADOS) as an intermediate value. Despite methodological and computational differences between the three models, resulting dose conversion factors do not appreciably differ from each other, although predictions by the two generation models are consistently smaller than that for the RADEP/IMBA model.

摘要

为了研究不同模型产生的剂量不确定性程度,对三种剂量测定模型进行了相互比较,它们代表不同类型的模型:(i)基于国际辐射防护委员会(ICRP)人类呼吸道模型的RADEP/IMBA模型,这是一个确定性区域隔室模型;(ii)RADOS模型,一个确定性气道生成模型;以及(iii)IDEAL剂量测定模型,一个随机气道生成模型。在三种不同水平上比较了这三种模型针对特定采矿暴露条件的输出结果:附着和未附着氡子体的沉积分数;核转变,反映沉积和清除的综合效应;以及由此产生的细胞剂量。由此产生的剂量暴露转换因子范围为7.8(中位数)mSv/WLM(IDEAL)至11.8 mSv/WLM(RADEP/IMBA),中间值为8.3 mSv/WLM(RADOS)。尽管这三种模型在方法和计算上存在差异,但由此产生的剂量转换因子彼此之间没有明显差异,尽管两个生成模型的预测结果始终小于RADEP/IMBA模型的预测结果。

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