Allerberger F, Kasten M J, Anhalt J P
Section of Clinical Microbiology, Mayo Clinic, Rochester, Minnesota.
Klin Wochenschr. 1991 Oct 31;69(17):813-6. doi: 10.1007/BF01744276.
During a six-year period five patients with Campylobacter fetus subspecies fetus infections were seen at the Mayo Clinic in Rochester, Minnesota. Bacteremia was observed in two patients, one presenting with aortic valve endocarditis and the other with abdominal atherosclerotic aortic aneurysm. C. fetus subsp. fetus was isolated from tibial tissue of a patient with osteomyelitis. Diarrhea was the main complaint of two further patients, and was also mentioned by the patient with the aortic aneurysm. Despite the use of incubation conditions and selective media geared to detect only Campylobacter jejuni, C. fetus subsp. fetus was isolated from stool specimens of the two patients with gastrointestinal symptoms. The fact that three of five C. fetus subsp. fetus infections observed in this study were associated with intestinal symptoms further supports the importance of the gastrointestinal tract in the pathogenesis of C. fetus subsp. fetus infections.
在六年期间,明尼苏达州罗切斯特市的梅奥诊所接诊了5例胎儿弯曲杆菌胎儿亚种感染患者。两名患者出现菌血症,其中一名患有主动脉瓣心内膜炎,另一名患有腹主动脉粥样硬化性动脉瘤。胎儿弯曲杆菌胎儿亚种从一名骨髓炎患者的胫骨组织中分离出来。另外两名患者的主要诉求是腹泻,腹主动脉瘤患者也提到了腹泻。尽管采用了仅用于检测空肠弯曲杆菌的培养条件和选择性培养基,但仍从两名有胃肠道症状患者的粪便标本中分离出了胎儿弯曲杆菌胎儿亚种。本研究中观察到的5例胎儿弯曲杆菌胎儿亚种感染中有3例与肠道症状相关,这一事实进一步证明了胃肠道在胎儿弯曲杆菌胎儿亚种感染发病机制中的重要性。