Department of Animal Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
J Exp Med. 1931 May 31;53(6):853-63. doi: 10.1084/jem.53.6.853.
A number of vibrios obtained from the small intestines of calves fed feces from spontaneous diarrhea in cows, natural intestinal disorders of calves, experimentally induced infections of calves, and cultures obtained from Dr. Theobald Smith have been studied. From the close morphological resemblance, similarities in motility, position and number of flagella, tinctorial properties, and the tendency to fragmentation in older cultures, as well as the narrow nutritive requirements, we are led to regard them as a closely allied group and we propose the name Vibrio jejuni. Immunologically as judged by agglutination the organisms have been divided into two groups, the smaller representing two strains originating from diarrhea in cows and the larger comprising one from this source and many from the calf disease. The larger group can be subdivided by means of agglutination absorption into cultures which do not contain the complete antigenic complex and others which do so. Certain freshly isolated vibrios when injected into rabbits incite definite reactions terminating in a localization in the small intestine accompanied by catarrhal inflammation.
已对从小牛粪便中获得的、从自然发生的牛腹泻、小牛肠道紊乱、实验诱导的小牛感染以及 Theobald Smith 博士培养的一些弧菌进行了研究。从形态上的密切相似性、运动性、鞭毛的位置和数量、染色特性以及在较老培养物中的碎片化趋势,以及狭窄的营养需求,我们认为它们是一个密切相关的群体,我们提议将其命名为空肠弧菌。根据凝集反应的免疫测定,这些生物体被分为两组,较小的一组代表两种源自牛腹泻的菌株,较大的一组包括一种源自该来源和许多源自小牛疾病的菌株。较大的组可以通过凝集吸收进一步分为不含有完整抗原复合物的培养物和含有完整抗原复合物的培养物。某些新分离的弧菌注射到兔子体内会引发明确的反应,最终导致小肠定位,并伴有卡他性炎症。