Indraccolo U, Cingolani N, Indraccolo S R
Department of Gynaecology, Perinatology and Child Welfare, II Faculty of Medicine and Surgery, La Sapienza University, Rome, Italy.
Eur J Gynaecol Oncol. 2007;28(3):233-4.
Brenner tumor is a rare ovarian neoplasm which is generally monolateral, more rarely bilateral, and often associated with endometrial disorders related to oestrogenic production. However, there is no considerable evidence that the possible oestrogenic production of this tumor may be the cause of endometrial disorders. A case of bilateral Brenner tumor with endometrial adenocarcinoma in a postmenopausal woman is presented and the features are briefly discussed, with the conclusion that hormone-producing Brenner tumors may exert their promoter effect on the development of endometrial carcinoma causing an imbalance in the oestrogen and progesterone ratio rather than producing a large amount of oestrogen.
勃勒纳瘤是一种罕见的卵巢肿瘤，通常为单侧性，双侧性更为罕见，且常与雌激素产生相关的子宫内膜疾病有关。然而，没有充分证据表明该肿瘤可能产生的雌激素是子宫内膜疾病的病因。本文报告一例绝经后妇女双侧勃勒纳瘤合并子宫内膜腺癌的病例，并简要讨论其特征，得出的结论是，产生激素的勃勒纳瘤可能对子宫内膜癌的发展发挥促进作用，导致雌激素和孕激素比例失衡，而非产生大量雌激素。
