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一名绝经后女性患子宫1级子宫内膜样腺癌伴大网膜转移及卵巢勃勒纳瘤的罕见病例。

A Rare Case of Grade 1 Endometrioid Adenocarcinoma of the Uterus With Omental Metastasis with Brenner Tumor of the Ovary in a Postmenopausal Female.

作者信息

Bagga Rashmi, Pandit Rubina, Saha Pradip Kumar, Kalra Jasvinder, Muthyala Tanuja, Gupta Nalini, Singh Tulika, Rai Bhavna

机构信息

Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India.

出版信息

J Midlife Health. 2020 Jan-Mar;11(1):45-48. doi: 10.4103/jmh.JMH_141_18. Epub 2020 May 4.

DOI:10.4103/jmh.JMH_141_18
PMID:32684728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7362985/
Abstract

Early-stage endometrial cancer may have microscopic omental metastases which is associated with a poor prognosis. There are no standard guidelines for omentectomy in early-stage endometrial cancer without risk factors. Brenner tumor is a rare ovarian tumor which is usually benign, but rarely, it may be malignant. Some Brenner tumors are endocrinologically active. Various studies have shown an association of Brenner tumor with endometrial hyperplasia, polyp, or early-stage carcinoma, probably due to its estrogen-secreting nature. We report a rare case of well-differentiated endometrioid adenocarcinoma of the uterus with <50% myometrial invasion with omental metastases associated with benign Brenner tumor of the ovary in a postmenopausal female.

摘要

早期子宫内膜癌可能存在微小的网膜转移,这与预后不良相关。对于无危险因素的早期子宫内膜癌,目前尚无网膜切除术的标准指南。勃勒纳瘤是一种罕见的卵巢肿瘤,通常为良性,但极少数情况下可能为恶性。一些勃勒纳瘤具有内分泌活性。各种研究表明,勃勒纳瘤与子宫内膜增生、息肉或早期癌有关,可能是由于其分泌雌激素的特性。我们报告了一例罕见病例,一名绝经后女性患有子宫高分化子宫内膜样腺癌,肌层浸润<50%,伴有网膜转移,并与卵巢良性勃勒纳瘤相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b800/7362985/b2a927456d43/JMH-11-45-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b800/7362985/b2a927456d43/JMH-11-45-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b800/7362985/b2a927456d43/JMH-11-45-g001.jpg

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本文引用的文献

1
Coexisting Brenner Tumor and Endometrial Carcinoma.并存的勃勒纳瘤和子宫内膜癌
J Midlife Health. 2017 Apr-Jun;8(2):89-91. doi: 10.4103/jmh.JMH_3_17.
2
Microscopic Omental Metastasis in Clinical Stage I Endometrial Cancer: A Meta-analysis.临床I期子宫内膜癌的微观网膜转移:一项Meta分析
Ann Surg Oncol. 2015 Oct;22(11):3695-700. doi: 10.1245/s10434-015-4443-1. Epub 2015 Feb 18.
3
Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study.卵巢交界性布伦纳瘤:一例免疫组织化学和分子研究病例报告
J Ovarian Res. 2014 Oct 29;7:101. doi: 10.1186/s13048-014-0101-7.
4
What is the importance of omental metastasis in patients with endometrial cancer?网膜转移在子宫内膜癌患者中具有何种重要性?
J Turk Ger Gynecol Assoc. 2014 Aug 8;15(3):164-72. doi: 10.5152/jtgga.2014.13109. eCollection 2014.
5
Brenner tumor of ovary: An incidental finding.卵巢布伦纳瘤:偶然发现。
J Midlife Health. 2011 Jan;2(1):40-1. doi: 10.4103/0976-7800.83273.
6
Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium.国际妇产科联盟(FIGO)对外阴癌、宫颈癌和子宫内膜癌分期的修订版。
Int J Gynaecol Obstet. 2009 May;105(2):103-4. doi: 10.1016/j.ijgo.2009.02.012.
7
Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study.子宫内膜癌系统性盆腔淋巴结清扫术的疗效(MRC ASTEC试验):一项随机研究
Lancet. 2009 Jan 10;373(9658):125-36. doi: 10.1016/S0140-6736(08)61766-3. Epub 2008 Dec 16.
8
Bilateral Brenner tumor with endometrial adenocarcinoma in a postmenopausal woman.一名绝经后女性患双侧勃勒纳瘤伴子宫内膜腺癌。
Eur J Gynaecol Oncol. 2007;28(3):233-4.
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Hormonal activity of Brenner tumors in postmenopausal women.绝经后女性中勃勒纳瘤的激素活性。
Am J Obstet Gynecol. 1962 Mar 1;83:666-73. doi: 10.1016/s0002-9378(16)35897-5.
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A case of estrogen-producing Brenner tumor with a stromal component as a potential source for estrogen.一例产生雌激素的勃勒纳瘤,其基质成分作为雌激素的潜在来源。
Oncology. 2002;63(2):201-4. doi: 10.1159/000063810.