Khwannimit Bodin
Division of Critical Care, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
J Med Assoc Thai. 2007 Jun;90(6):1074-81.
To compare the validity of the Multiple Organ Dysfunction Score (MODS), Sequential Organ Failure Assessment (SOFA), and Logistic Organ Dysfunction Score (LOD) for predicting ICU mortality of Thai critically ill patients.
A retrospective study was made of prospective data collected between the 1st July 2004 and 31st March 2006 at Songklanagarind Hospital.
One thousand seven hundred and eighty two patients were enrolled in the present study. Two hundred and ninety three (16.4%) deaths were recorded in the ICU. The areas under the Receiver Operating Curves (A UC) for the prediction of ICU mortality the results were 0.861 for MODS, 0.879 for SOFA and 0.880 for LOD. The AUC of SOFA and LOD showed a statistical significance higher than the MODS score (p = 0.014 and p = 0.042, respectively). Of all the models, the neurological failure score showed the best correlation with ICU mortality.
All three organ dysfunction scores satisfactorily predicted ICU mortality. The LOD and neurological failure had the best correlation with ICU outcome.
比较多器官功能障碍评分（MODS）、序贯器官衰竭评估（SOFA）和逻辑器官功能障碍评分（LOD）预测泰国重症患者重症监护病房（ICU）死亡率的有效性。
对2004年7月1日至2006年3月31日在宋卡那卡林医院收集的前瞻性数据进行回顾性研究。
本研究纳入了1782例患者。ICU记录到293例（16.4%）死亡。预测ICU死亡率的受试者工作特征曲线（ROC）下面积（AUC）结果为：MODS为0.861，SOFA为0.879，LOD为0.880。SOFA和LOD的AUC显示出统计学意义上高于MODS评分（分别为p = 0.014和p = 0.042）。在所有模型中，神经功能衰竭评分与ICU死亡率的相关性最佳。
所有三种器官功能障碍评分均能令人满意地预测ICU死亡率。LOD和神经功能衰竭与ICU结局的相关性最佳。
