Dogan M Cem, Leblebisatan Goksel, Haytac M Cenk, Antmen Bulent, Surmegozler Onur
Cukurova University, Faculty of Dentistry, Department of Pediatric Hematology, Balcali, Adana, Turkey.
Quintessence Int. 2007 Jun;38(6):515-20.
Mucormycosis is a rare acute opportunistic infection caused by a saprophytic fungus, which belongs to the order Mucorales. This report describes intraoral mucormycosis in 2 children with acute leukemia who were undergoing chemotherapy and had febrile neutropenia. A 7-year-old boy with acute myeloid leukemia and a 9-year-old boy with acute lymphoblastic leukemia were referred to the Department of Pediatric Dentistry at Cukurova University for their intraoral soft tissue lesions, which were diagnosed as mucormycosis by histologic examination. While, for the first case, the lesion was debrided under general anesthesia and medical antifungal therapy was performed, only medical management was done, without any debridement, for the second case. Early recognition of mucormycosis is necessary to limit the spread of infection, which can lead to high morbidity and mortality. Therefore, health practitioners should be familiar with the signs and symptoms of the disease.
毛霉病是一种由腐生真菌引起的罕见急性机会性感染，该真菌属于毛霉目。本报告描述了2例正在接受化疗且患有发热性中性粒细胞减少症的急性白血病患儿的口腔内毛霉病。一名患有急性髓系白血病的7岁男孩和一名患有急性淋巴细胞白血病的9岁男孩因口腔软组织病变被转诊至库库洛瓦大学儿科牙科，经组织学检查诊断为毛霉病。对于第一例病例，在全身麻醉下对病变进行清创并进行了抗真菌药物治疗，而对于第二例病例，仅进行了药物治疗，未进行任何清创。早期识别毛霉病对于限制感染扩散至关重要，感染扩散可导致高发病率和死亡率。因此，医护人员应熟悉该疾病的体征和症状。
