[采用绒毛膜绒毛直接制片法对自然流产进行染色体分析]
[Chromosome analysis in spontaneous abortion using direct preparation of chorionic villi].
作者信息
Gardó S, Bajnóczky K
机构信息
Györ-Moson-Sopron Megyei Kórház.
出版信息
Orv Hetil. 1991 Dec 8;132(49):2727-9.
Two hundred cases of spontaneous abortions were studied by analysing chromosomes directly from chorionic villi. Abnormal karyotypes were found in 52% of the investigated cases. Among the chromosome abnormalities the most frequent were the trisomies (56.7%) followed by polyploidy (23.1%), monosomy X (15.4%) and structural anomalies (4.8%). The rapid and relatively simple method is suitable for studying the causes of spontaneous abortions, and these information may be helpful also for genetic counselling.
通过直接分析绒毛膜绒毛的染色体，对200例自然流产病例进行了研究。在52%的被调查病例中发现了异常核型。在染色体异常中，最常见的是三体性（56.7%），其次是多倍体（23.1%）、X单体（15.4%）和结构异常（4.8%）。这种快速且相对简单的方法适用于研究自然流产的原因，这些信息对遗传咨询也可能有帮助。
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