Brewer Noel T, Fazekas Karah I
Department of Health Behavior and Health Education, School of Public Health, University of North Carolina, 306 Rosenau Hall CB 7440, Chapel Hill, NC 27516, USA.
Prev Med. 2007 Aug-Sep;45(2-3):107-14. doi: 10.1016/j.ypmed.2007.05.013. Epub 2007 Jun 2.
To inform future human papillomavirus (HPV) vaccination programs, we systematically reviewed studies of HPV-related beliefs and HPV vaccine acceptability, organizing the findings using health behavior theory and cervical cancer risk factors.
We searched Medline, CINAHL, and PsycINFO from 1995 to January, 2007 for studies of HPV beliefs and HPV vaccine acceptability among adolescents, young adults, and parents of adolescents in the United States.
We identified 28 studies. Most were small, cross-sectional studies of parents and adults. Most parents reacted positively to the possibility of vaccinating their daughters against HPV. Vaccination acceptability was higher when people believed the vaccine was effective, a physician would recommend it, and HPV infection was likely. Cost and, for 6% to 12% of parents, concerns that vaccination would promote adolescent sexual behavior were barriers to vaccination. African American, Hispanic, and white respondents were equally accepting of the HPV vaccine. Parents with lower levels of education reported higher vaccine acceptability. Many studies inadequately reported on other variables associated with cervical cancer mortality.
HPV vaccine programs in the United States should emphasize high vaccine effectiveness, the high likelihood of HPV infection, and physicians' recommendations, and address barriers to vaccination.
为指导未来的人乳头瘤病毒（HPV）疫苗接种计划，我们系统回顾了关于HPV相关认知及HPV疫苗可接受性的研究，并运用健康行为理论和宫颈癌风险因素对研究结果进行整理。
我们检索了1995年至2007年1月期间的Medline、CINAHL和PsycINFO数据库，查找关于美国青少年、青年及青少年家长对HPV的认知和HPV疫苗可接受性的研究。
我们共识别出28项研究。多数为针对家长和成年人的小型横断面研究。多数家长对为女儿接种HPV疫苗的可能性反应积极。当人们认为疫苗有效、医生会推荐接种且HPV感染可能性较大时，疫苗可接受性更高。成本以及6%至12%的家长担心接种疫苗会促使青少年发生性行为，这些都是疫苗接种的障碍。非裔美国人、西班牙裔和白人受访者对HPV疫苗的接受程度相当。教育程度较低的家长报告的疫苗可接受性更高。许多研究对与宫颈癌死亡率相关的其他变量报告不足。
美国的HPV疫苗接种计划应强调疫苗的高效性、HPV感染的高可能性以及医生的建议，并消除疫苗接种的障碍。
