Solorio Dionicio Martinez, Jennings Michael P
Department of Chemistry, 500 Campus Drive, The University of Alabama, Tuscaloosa, Alabama 35487-0336, USA.
J Org Chem. 2007 Aug 17;72(17):6621-3. doi: 10.1021/jo071035l. Epub 2007 Jul 14.
The first total synthesis and absolute configuration of bruguierol C are reported. The key step involved the diastereoselective capture of an in situ generated oxocarbenium ion via an intramolecular Friedel-Crafts alkylation.
报道了布鲁吉罗醇C的首次全合成及其绝对构型。关键步骤涉及通过分子内傅克烷基化非对映选择性捕获原位生成的氧鎓离子。
